(T. G. Br.)
Pathology of the Blood.
The changes in the blood in disease are probably as numerous and varied as the diseases which attack the body, for the blood is not only the medium of respiration, but also of nutrition, of defence against organisms and of many other functions, none of which can be affected without corresponding alterations occurring in the circulating fluid. The immense majority of these changes are, however, so subtle that they escape detection by our present methods. But in certain directions, notably in regard to the relations with micro-organisms, changes in the blood-plasma can be made out, though they are not associated in all cases with changes in the formed elements which float in it, nor with any obvious microscopical or chemical alterations.
The phenomena of immunity to the attacks of bacteria or their toxins, of agglutinative action, of opsonic action, of the precipitin tests, and of haemolysis, are all largely dependent on the inherent or acquired charactersImmunity.of the blood serum. It is a commonplace that different people vary in their susceptibility to the attacks of different organisms, and different species of animals also vary greatly. This “natural immunity” is due partly to the power possessed by the leucocytes or white blood corpuscles of taking into their bodies and digesting or holding in an inert state organisms which reach the blood—phagocytosis,—partly to certain bodies in the blood serum which have a bactericidal action, or whose presence enables the phagocytes to deal more easily with the organisms. This natural immunity can be heightened when it exists, or an artificial immunity can be produced in various ways. Doses of organisms or their toxins can be injected on one or several occasions, and provided that the lethal dose be not reached, in most cases an increased power of resistance is produced. The organisms may be injected alive in a virulent condition, or with their virulence lessened by heat or cold, by antiseptics, by cultivation in the presence of oxygen, or by passage through other animals, or they may first be killed, or their toxins alone injected. The method chosen in each case depends on the organism dealt with. The result of this treatment is that in the animal treated protective substances appear in the serum, and these substances can be transferred to the serum of another animal or of man; in other words the active immunity of the experimental animal can be translated intothe passive immunity of man. According to the nature of the substances injected into the former, its serum may be antitoxic, if it has been immunized against any particular toxin, or antibacterial, if against an organism. Familiar examples of these are, of the former diphtheria antitoxin, of the latter anti-plague and anti-typhoid sera. An antitoxin exerts its effects by actual combination with the respective toxin, the combination being inert. It is probable that the ultimate source of the antitoxin is to be found in the living cells of the tissues and that it passes from them into the blood. The action of an antibacterial serum depends on the presence in it of a substance known as “immune-body,” which has a special affinity and power of combining with the bacterium used. In order that it may exert this power it requires the presence of a substance normally present in the serum known as “complement.” The development of these “anti-bodies,” though it has been studied mainly in connexion with bacteria and their toxins, is not confined to their action, but can be demonstrated in regard to many other substances, such as ferments, tissue cells, red corpuscles, &c. In some animals, for example, the blood serum has the power of dissolving the red corpuscles of an animal of different species;e.g.the guinea-pig’s serum is “haemolytic” to the red corpuscles of the ox. This haemolytic power (haemolysis) can be increased by repeated injections of red corpuscles from the other animal, in this case also, as in the bacterial case, by the production and action of immune-body and complement. The antiserum produced in the case of the red corpuscles may sometimes, if injected into the first animal, whose red corpuscles were used, cause extensive destruction of its red corpuscles, with haemoglobinuria, and sometimes a fatal result.
Opsonic action depends on the presence of a substance, the “opsonin,” in the serum of an immunized animal, which makes the organism in question more easily taken up by the phagocytes (leucocytes) of the blood. The opsonin becomes fixed to the organisms. It is present to a certain extent in normal serum, but can be greatly increased by the process of immunization; and the “opsonic index,” or relation between the number of organisms taken up by leucocytes when treated with the serum of a healthy person or “control,” and with the serum of a person affected with any bacterial disease and under treatment by immunization, is regarded by some as representing the degree of immunity produced.
Agglutinative action is evidence of the presence in a serum of a somewhat similar set of substances, known as “agglutinins.” When a portion of an antiserum is added to an emulsion of the corresponding organism, the organisms, if they are motile, cease to move, and in any case become gathered together into clumps. In all probability several different bodies are concerned in this process. This reaction, in its practical applications at least, may be regarded as a reaction of infection rather than of immunization as ordinarily understood, for it is found that the blood serum of patients suffering from typhoid, Malta fever, cholera, and many other bacterial diseases, agglutinates the corresponding organisms. This fact has come to be of great importance in diagnosis.
The precipitin test depends on a somewhat analogous reaction. If the serum of an animal be injected repeatedly into another animal of different species, a “precipitin” appears in the serum of the animal treated, which causes a precipitate when added to the serum of the first animal. The special importance of this fact is that it can be utilized as a method of distinguishing between human blood and that of animals, which is often of importance in medical jurisprudence.
In this summary the facts adduced are practically all biological, and are due to the extraordinary activity with which the study of bacteriology (q.v.) has been pursued in recent years. The chemistry of the blood has not hitherto been found to give information of clinical or diagnostic importance, and nothing need here be added to what is said above on the physiology of the blood. Enough has been said, however, to show the extraordinary complexity of the apparently simple blood serum.
The methods at present employed in examining the blood clinically are: the enumeration of the red and white corpuscles per cubic millimetre; the estimation of the percentage of haemoglobin and of the specific gravity of the blood; the microscopic examination of freshly-drawn blood and of blood films made upon cover-glasses, fixed and stained. In special cases the alkalinity and the rapidity of coagulation may be ascertained, or the blood may be examined bacteriologically. We have no universally accepted means of estimating, during life, the total amount of blood in the body, though the method of J.S. Haldane and J. Lorrain Smith, in which the total oxygen capacity of the blood is estimated, and its total volume worked out from that datum, has seemed to promise important results (Journ. of Physiol. vol. xxv. p. 331, 1900). After death the amount of blood sometimes seems to be increased, and sometimes, as in “pernicious anaemia,” it is certainly diminished. But the high counts of red corpuscles which are occasionally reported as evidence of plethora or increase of the total blood are really only indications of concentration of the fluid except in certain rare cases. It is necessary, therefore, in examining blood diseases, to confine ourselves to the study of the blood-unit, which is always taken as the cubic millimetre, without reference to the number of units in the body.
Anaemiais often used as a generic term for all blood diseases, for in almost all of them the haemoglobin is diminished, either as a result of diminution in the number of the red corpuscles in which it is contained, or because theAnaemia.individual red corpuscles contain a smaller amount of haemoglobin than the normal. As haemoglobin is the medium of respiratory interchange, its diminution causes obvious symptoms, which are much more easily appreciated by the patient than those caused by alterations in the plasma or the leucocytes. It is customary to divide anaemias into “primary” and “secondary”: the primary are those for which no adequate cause has as yet been discovered; the secondary, those whose cause is known. Among the former are usually included chlorosis, pernicious anaemia, and sometimes the leucocythaemias; among the latter, the anaemias due to such agencies as malignant disease, malaria, chronic metallic poisoning, chronic haemorrhage, tubercle, Bright’s disease, infective processes, intestinal parasites, &c. As our knowledge advances, however, this distinction will probably be given up, for the causes of several of the primary anaemias have been discovered. For example, the anaemia due tobothriocephalus, an intestinal parasite, is clinically indistinguishable from the other forms of pernicious anaemia with which it used to be included, and leucocythaemia has been declared by Löwit, though probably erroneously, to be due to a blood parasite closely related to that of malaria. In all these conditions there is a considerable similarity in the symptoms produced and in the pathological anatomy. The general symptoms are pallor of the skin and mucous membranes, weakness and lassitude, shortness of breath, palpitation, a tendency to fainting, and usually also gastro-intestinal disturbance, headache and neuralgia. The heart is often dilated, and on auscultation the systolic murmurs associated with that condition are heard. In fatal cases the internal organs are found to be pale, and very often their cells contain an excessive amount of fat. In many anaemias there is a special tendency to haemorrhage. Most of the above symptoms and organic changes are directly due to diminished respiratory interchange from the loss of haemoglobin, and to its effect on the various organs involved. The diagnosis depends ultimately in all cases upon the examination of the blood.
Though the relative proportions of the leucocytes are probably continually undergoing change even in health, especially as the result of taking food, the number of red corpuscles remains much more constant. Through the agency of some unknown mechanism, the supply of fresh red corpuscles from the bone-marrow keeps pace with the destruction of effete corpuscles, and in health each corpuscle contains a definite and constant amount of haemoglobin. The disturbance of this arrangement in anaemia may be due to loss or to increased destruction of corpuscles, to the supply of a smaller number of new ones, to adiminution of the amount of haemoglobin in the individual new corpuscles, or to a combination of these causes. It is most easy to illustrate this by describing what happens after a haemorrhage. If this is small, the loss is replaced by the fully-formed corpuscles held in reserve in the marrow, and there is no disturbance. If it is larger, the amount of fluid lost is first made up by fluid drawn from the tissues, so that the number of corpuscles is apparently diminished by dilution of the blood; the erythroblasts, or formative red corpuscles, of the bone-marrow are stimulated to proliferation, and new corpuscles are quickly thrown into the circulation. These are apt, however, to be small and to contain a subnormal amount of haemoglobin, and it is only after some time that they are destroyed and their place taken by normal corpuscles. If the loss has been very great, nucleated red corpuscles may even be carried into the blood-stream. The blood possesses a great power of recovery, if time be given it, because the organ (bone-marrow) which forms so many of its elements never, in health, works at high pressure. Only a part of the marrow, the so-called red marrow, is normally occupied by erythroblastic tissue, the rest of the medullary cavity of the bones being taken up by fat. If any long-continued demand for red corpuscles is made, the fat is absorbed, and its place gradually taken by red marrow. This compensatory change is found in all chronic anaemias, no matter what their cause may be, except in some rare cases in which the marrow does not react.
It is often very difficult, especially in “secondary” anaemias, to say which of the above processes is mainly at work. In acute anaemias, such as those associated with septicaemia, there is no doubt that blood destruction plays the principal part. But if the cause of anaemia is a chronic one, a gastric cancer, for instance, though there may possibly be an increased amount of destruction of corpuscles in some cases, and though there is often loss by haemorrhage, the cancer interferes with nutrition, the blood is impoverished and does not nourish the erythroblasts in the marrow sufficiently, and the new corpuscles which are turned out are few and poor in haemoglobin. In chronic anaemias, regeneration always goes on side by side with destruction, and it is important to remember that the state of the blood in these conditions gives the measure, not of the amount of destruction which is taking place so much as of the amount of regeneration of which the organism is capable. The evidence of destruction has often to be sought for in other organs, or in secretions or excretions.
Of the so-called primary anaemias the most common ischlorosis, an anaemia which occurs only in the female sex, between the ages of fifteen and twenty-five as a rule. Its symptoms are those caused by a diminution of haemoglobin, and though it is never directly fatal, and is extremely amenable to treatment with iron preparations, its subjects very frequently suffer from relapses at varying intervals after the first attack. Its causation is probably complex. Bad hygienic conditions, over-fatigue, want of proper food, especially of the iron-containing proteids of meat, the strain put upon the blood and blood-forming organs by the accession of puberty and the occurrence of menstruation, all probably play a part in it. It has also been suggested that internal secretions may be concerned in stimulating the bone-marrow, and that in the female sex in particular the genital organs may act in this way. Imperfect assumption of function by these organs at puberty, caused perhaps by some of the above-mentioned conditions, might lead to sluggishness in the bone-marrow, and to the supply to the blood of the poorly-formed corpuscles deficient in haemoglobin which are characteristic of the disease. Chlorosis is the type of anaemias from imperfect blood-formation. Lorrain Smith has produced evidence to show that the total amount of haemoglobin in the body is not diminished in this disease, but that the blood-plasma is greatly increased in amount, so that the haemoglobin is diluted and the amount in each blood-unit greatly lessened.
Pernicious anaemiais a rarer disease than chlorosis, occurs usually later in life, and is distributed nearly equally between the two sexes. But it is of great importance because of its almost uniformly fatal termination, though its downward course is generally broken by temporary improvement on one or more occasions. The symptoms are those of a progressive anaemia, in which gastro-intestinal disturbance usually plays a large part, and nervous symptoms are common, and they become at last much more severe than those of any secondary anaemia. The patient may die in the first attack, but more usually, when things seem to be at their worst, improvement sets in, either spontaneously or as the result of treatment, and the patient slowly regains apparent health. This remission may be followed by a relapse, that again by a remission, and so on, but as a rule the disease is fatal within, at the outside, two or three years.
The prime cause of the disease is not known. It seems probable indeed that the causal factors are numerous. Severe malarial infection, syphilis, pregnancy, chronic gastro-intestinal disease, chronic gas-poisoning, are all, in different cases, known to have been causally associated with it, and it is probable that a congenital weakness of the bone-marrow has often to do with its production, as in many cases a family or hereditary history of the disease can be obtained. The condition is now regarded as a chronic toxaemia, partly because of the clinical symptoms and pathological appearances, partly because analogous conditions can be produced experimentally by such poisons as saponin and toluylendiamin, and partly because of the facts ofbothriocephalusanaemia. The site of production of the toxin, or toxins, for it is possible that several may have the same effect on the blood, is possibly not always the same, but must often be the alimentary canal, asbothriocephalusanaemia proves. Not all persons affected with this intestinal tapeworm contract the disease, but only those in whose intestines the worm is dead and decomposing or sometimes only “sick.” The expulsion of the worm puts an end to the absorption of the toxin and the patients recover. No adequate explanation of the formation of the toxin in the immense majority of the cases, in which there is no tapeworm, has yet been given. It is certain that no organism as yet known is concerned.
This toxaemia affects the marrow and through it the blood, the gastro-intestinal apparatus and the nervous system, especially the spinal cord, in different proportions in different cases. The effect upon the marrow is to alter the type of red corpuscle formation, causing a reversion to the embryonic condition, in which the nucleated red corpuscles are large (megaloblasts), and the corpuscles in the blood formed from them are also large, are apparently ill suited to the needs of the adult, and easily break down, as the deposits of iron in the liver, spleen, kidneys and marrow prove. Whether this reversion is due to an exhaustion of the normal process or to an inhibition of it is not definitely known. The result is that the circulating red corpuscles are enormously diminished; it is usual to find 1,000,000 or less in the cubic millimetre instead of the normal 5,000,000. Though the haemoglobin is of course absolutely diminished, it is always, in severe cases, present in relatively higher percentage than the red corpuscles, because the average red corpuscle is larger and contains more haemoglobin than the normal. The large nucleated red corpuscles (megaloblasts) with which the marrow is crowded, often appear in the blood.
Other anaemias, such as those known aslymphadenoma, or Hodgkin’s disease,splenic anaemia,chloroma,leucanaemiaand theanaemia pseudo-leucaemicaof children, need not be described here, as they are either rare or their occurrence or nature is still too much under discussion.
The number and nature of the leucocytes in the blood bears no constant or necessary relation to the number or condition of the red corpuscles, and their variations depend on entirely different conditions. The number in theLeucocytosis.cubic millimetre is usually about 7000, but may vary in health from 5000 to 10,000. A diminution in their number is known asleucopenia, and is found in starvation, in some infective diseases, as for example in typhoid fever, in malaria and Malta fever, and in pernicious anaemia. An increase is very much more frequent, and is known asleucocytosis, though in this term is usually connoted a relative increase in the proportion of the polymorphonuclear neutrophile leucocytes.Leucocytosis occurs under a great variety of conditions, normally to a slight extent during digestion, during pregnancy, and after violent exercise, and abnormally after haemorrhage, in the course of inflammations and many infective diseases, in malignant disease, in such toxic states as uraemia, and after the ingestion of nuclein and other substances. It does not occur in some infective diseases, the most important of which are typhoid fever, malaria, influenza, measles and uncomplicated tuberculosis. In all cases where it is sufficiently severe and long continued, the reserve space in the bone-marrow is filled up by the active proliferation of the leucocytes normally found there, and is used as a nursery for the leucocytes required in the blood. In many cases leucocytosis is known to be associated with the defence of the organism from injurious influences, and its amount depends on the relation between the severity of the attack and the power of resistance. There may be an increase in the proportions present in the blood of lymphocytes (lymphocytosis), and of eosinophile cells (eosinophilia). This latter change is associated specially with some forms of asthma, with certain skin diseases, and with the presence of animal parasites in the body, such as ankylostoma and filaria.
The disease in which the number of leucocytes in the blood is greatest isleucocythaemiaor leucaemia. There are two main forms of this disease, in both of which there are anaemia, enlargement of the spleen and lymphaticLeucaemia.glands, or of either of them, leucocytic hypertrophy of the bone-marrow, and deposits of leucocytes in the liver, kidney and other organs. The difference lies in the kind of leucocytes present in excess in the blood, blood-forming organs and deposits in the tissues. In the one form these are lymphocytes, which are found in health mainly in the marrow, the blood itself, the lymph glands and in the lymphatic tissue round the alimentary canal; in the other they are the kinds of leucocytes normally found in the bone-marrow-myelocytes, neutrophile, basophile and eosinophile, and polymorphonuclear cells, also neutrophile, basophile and eosinophile. The clinical course of the two forms may differ. The first, known as lymphatic leucaemia orlymphaemia, may be acute, and prove fatal in a few weeks or even days with rapidly advancing anaemia, or may be chronic and last for one or two years or longer. The second, known as spleno-myelogenous leucaemia ormyelaemia, is almost always chronic, and may last for several years. Recovery does not take place, though remissions may occur. The use of the X-rays has been found to influence the course of this disease very favourably. The most recent view of the pathology of the disease is that it is due to an overgrowth of the bone-marrow leucocytes, analogous in some respects to tumour growth and caused by the removal of some controlling mechanism rather than by stimulation. The anaemia accompanying the disease is due partly to the leucocyte overgrowth, which takes up the space in the marrow belonging of right to red corpuscle formation and interferes with it.
(G. L. G.)
1The suffix-phile, Greekφιλεῖν, to love, prefer, is in scientific terminology frequently applied to substances that exhibit such preference for particular stains or reagents, the names of which form the first part of the word.
1The suffix-phile, Greekφιλεῖν, to love, prefer, is in scientific terminology frequently applied to substances that exhibit such preference for particular stains or reagents, the names of which form the first part of the word.
BLOOD-LETTING.There are certain morbid conditions when a patient may obtain marked relief from the abstraction of a certain amount of blood, from three or four ounces up to twenty or even thirty in extreme cases. This may be effected by venesection, or the application of leeches, or more rarely by cupping (q.v.). Unfortunately, in years gone by, blood-letting was used to such excess, as a cure for almost every known disease, that public opinion is now extremely opposed to it. In certain pathological conditions, however, it brings relief and saves life when no other means would act with sufficient promptness to take its place.
Venesection, in which the blood is usually withdrawn from the median-basilic vein of the arm, has the disadvantage that it can only be performed by the medical man, and that the patient’s friends are generally very much opposed to the idea. But the public are not nearly so prejudiced against the use of leeches; and as the nurse in charge can be instructed to use these if occasion arises, this is the form of blood-letting usually practised to-day. From one to twelve leeches are applied at the time, the average leech withdrawing some two drachms of blood. Should this prove insufficient, as much again can be abstracted by the immediate application of hot fomentations to the wounds. They should always be applied over some bony prominence, that pressure may be effectively used to stop the haemorrhage afterwards. They should never be placed over superficial veins, or where there is much loose subcutaneous tissue. If, as is often the case, there is any difficulty in making them bite, the skin should be pricked at the desired spot with the point of a sterilized needle, and the leech will then attach itself without further trouble. Also they must be left to fall off of their own accord, the nurse never dragging them forcibly off. If cold and pressure fail to stop the subsequent haemorrhage, a little powdered alum or other styptic may be inserted in the wound. The following are the main indications for their use, though in some cases they are better replaced by venesection, (1) For stagnation of blood on the right side of the heart with constant dyspnoea, cyanosis, &c. In acute lung disease, the sudden obstruction to the passage of blood through the lungs throws such an increased strain on the right ventricle that it may dilate to the verge of paralysis; but by lessening the total volume of blood, the heart’s work is lightened for a time, and the danger at the moment tided over. This is a condition frequently met with in the early stages of acute pneumonia, pleurisy and bronchitis, when the obstruction is in the lungs, the heart being normal. But the same result is also met with as a result of failure of compensation with back pressure in certain forms of heart disease (q.v.). (2) To lower arterial tension. In the early stages of cerebral haemorrhage (before coma has supervened), when the heart is working vigorously and the tension of the pulse is high, a timely venesection may lead to arrest of the haemorrhage by lowering the blood pressure and so giving the blood in the ruptured vessel an opportunity to coagulate. (3) In various convulsive attacks, as in acute uraemia.
BLOOD-MONEY,colloquially, the reward for betraying a criminal to justice. More strictly it is used of the money-penalty paid in old days by a murderer to the kinsfolk of his victim. These fines completely protected the offender from the vengeance of the injured family. The system was common among the Scandinavian and Teutonic races previous to the introduction of Christianity, and a scale of payments, graduated according to the heinousness of the crime, was fixed by laws, which further settled who could exact the blood-money, and who were entitled to share it. Homicide was not the only crime thus expiable: blood-money could be exacted for all crimes of violence. Some acts, such as killing any one in a church or while asleep, or within the precincts of the royal palace, were “bot-less”; and the death penalty was inflicted. Such a criminal was outlawed, and his enemies could kill him wherever they found him.
BLOODSTONE,the popular name of the mineral heliotrope, which is a variety of dark green chalcedony or plasma, with bright red spots, splashes and streaks. The green colour is due to a chloritic mineral; the red to haematite. Some coarse kinds are opaque, resembling in this respect jasper, and some writers have sought to restrict the name “bloodstone” to green jasper, with red markings, thus making heliotrope a translucent and bloodstone an opaque stone, but, though convenient, such a distinction is not generally recognized. A good deal of bloodstone comes from India, where it occurs in the Deccan traps, and is cut and polished at Cambay. The stone is used for seals, knife-handles and various trivial ornaments. Bloodstone is not very widely distributed, but is found in the basaltic rocks of the Isle of Rum in the west of Scotland, and in a few other localities. Haematite (Gr.αἷμα, blood), or native peroxide of iron, is also sometimes called “bloodstone.”
BLOOM(from A.S.blôma, a flower), the blossom of flowering plants, or the powdery film on the skin of fresh-picked fruit; hence applied to the surface of newly-minted coins or to a cloudy appearance on the varnish of painting due to moisture; also, in metallurgy, a term used of the rough billets of iron and steel, which have undergone a preliminary hammering or rolling, and are ready for further working.
BLOOMER, AMELIA JENKS(1818-1894), American dress-reformer and women’s rights advocate, was born at Homer, NewYork, on the 27th of May 1818. After her marriage in 1840 she established a periodical calledThe Lily, which had some success. In 1849 she took up the idea—previously originated by Mrs Elizabeth Smith Miller—of a reform in woman’s dress, and the wearing of a short skirt, with loose trousers, gathered round the ankles. The name of “bloomers” gradually became popularly attached to any divided-skirt or knickerbocker dress for women. Until her death on the 30th of December 1894 Mrs Bloomer took a prominent part in the temperance campaign and in that for woman’s suffrage.
BLOOMFIELD, MAURICE(1855- ), American Sanskrit scholar, was born on the 23rd of February 1855, in Bielitz, Austrian Silesia. He went to the United States in 1867, and ten years later graduated from Furman University, Greenville, South Carolina. He then studied Sanskrit at Yale, under W.D. Whitney, and at Johns Hopkins, to which university he returned as associate professor in 1881 after a stay of two years in Berlin and Leipzig, and soon afterwards was promoted professor of Sanskrit and comparative philology. His papers in theAmerican Journal of Philologynumber a few in comparative linguistics, such as those on assimilation and adaptation in congeneric classes of words, and many valuable “Contributions to the Interpretation of the Vedas,” and he is best known as a student of the Vedas. He translated, for Max-Müller’sSacred Books of the East, the Hymns of the Atharva-Veda (1897); contributed to the Bühler-KielhornGrundriss der indo-arischen Philologie und Altertumskundethe section “The Atharva-Veda and the Gopatha Brahmana” (1899); was first to edit the Kauçika-Sutra (1890), and in 1907 published, in the Harvard Oriental series,A Vedic Concordance. In 1905 he publishedCerberus, the Dog of Hades, a study in comparative mythology.
BLOOMFIELD, ROBERT(1766-1823), English poet, was born of humble parents at the village of Honington, Suffolk, on the 3rd of December 1766. He was apprenticed at the age of eleven to a farmer, but he was too small and frail for field labour, and four years later he came to London to work for a shoemaker. The poem that made his reputation,The Farmer’s Boy, was written in a garret in Bell Alley. The manuscript, declined by several publishers, fell into the hands of Capell Lofft, who arranged for its publication with woodcuts by Bewick in 1800. The success of the poem was remarkable, over 25,000 copies being sold in the next two years. His reputation was increased by the appearance of hisRural Tales(1802),News from the Farm(1804),Wild Flowers(1806) andThe Banks of the Wye(1811). Influential friends attempted to provide for Bloomfield, but ill-health and possibly faults of temperament prevented the success of these efforts, and the poet died in poverty at Shefford, Bedfordshire, on the 19th of August 1823. HisRemains in Poetry and Verseappeared in 1824.
BLOOMFIELD,a town of Essex county, New Jersey, U.S.A., about 12 m. W. of New York, and directly adjoining the city of Newark on the N. Pop. (1900) 9668, of whom 2267 were foreign-born; (1905, state census) 11,668; (1910), 15,070. Area, 5.42 sq. m. Bloomfield is served by the Erie, and the Delaware, Lackawanna & Western railways, and by several electric lines connecting with Newark, Montclair, Orange, East Orange and other neighbouring places. It is a residential suburb of Newark and New York, is the seat of a German theological school (Presbyterian, 1869) and has the Jarvie Memorial library (1902). There is a Central Green, and in 1908 land was acquired for another park. Among the town’s manufactures are silk and woollen goods, paper, electric elevators, electric lamps, rubber goods, safety pins, hats, cream separators, brushes and novelties. The value of the town’s factory products increased from $3,370,924 in 1900 to $4,645,483 in 1905, or 37.8%. First settled about 1670-1675 by the Dutch and by New Englanders from the Newark colony, Bloomfield was long a part of Newark, the principal settlement at first being known as Wardsesson. In 1796 it was named Bloomfield in honour of General Joseph Bloomfield (1753-1823), who served (1775-1778) in the War of American Independence, reaching the rank of major, was governor of New Jersey in 1801-1802 and 1803-1812, brigadier-general in the United States army during the War of 1812, and a Democratic representative in Congress from 1817 to 1821. The township of Bloomfield was incorporated in 1812. From it were subsequently set off Belleville (1839), Montclair (1868) and Glen Ridge (1895).
BLOOMINGTON,a city and the county-seat of McLean county, Illinois, U.S.A., in the central part of the state, about 125 m. S.W. of Chicago. Pop. (1890) 20,484; (1900) 23,286, of whom 3611 were foreign-born, there being a large German element; (1910 census) 25,768. The city is served by the Chicago & Alton, the Illinois Central, the Cleveland, Chicago, Cincinnati & St Louis, and the Lake Erie & Western railways, and by electric inter-urban lines. Bloomington is the seat of the Illinois Wesleyan University (Methodist Episcopal, co-educational, founded in 1850), which comprises a college of liberal arts, an academy, a college of law, a college of music and a school of oratory, and in 1907 had 1350 students. In the town ofNormal(pop. in 1900, 3795), 2 m. north of Bloomington, are the Illinois State Normal University (opened at Bloomington in 1857 and removed to its present site in 1860), one of the first normal schools in the Middle West, and the state soldiers’ orphans’ home (1869). Bloomington has a public library, and Franklin and Miller parks; among its principal buildings are the court house, built of marble, and the Y.M.C.A. building. Among the manufacturing establishments are foundries and machine shops, including the large shops of the Chicago & Alton railway, slaughtering and meat-packing establishments, flour and grist mills, printing and publishing establishments, a caramel factory and lumber factories. The value of the city’s factory products increased from $3,011,899 in 1900 to $5,777,000 in 1905, or 91.8%. There are valuable coal mines in and near the city, and the city is situated in a fine farming region. Bloomington derives its name from Blooming Grove, a small forest which was crossed by the trails leading from the Galena lead mines to Southern Illinois, from Lake Michigan to St Louis, and from the Eastern to the far Western states. The first settlement was made in 1822, but the town was not formally founded until 1831, when it became the county-seat of McLean county. The first city charter was obtained in 1850, and in 1857 the public school system was established. In 1856 Bloomington was the meeting place of a state convention called by the Illinois editors who were opposed to the Kansas-Nebraska Bill (see DECATUR). This was the first convention of the Republican party in Illinois; among the delegates were Abraham Lincoln, Richard Yates, John M. Palmer and Owen Lovejoy. The city has been the residence of a number of prominent men, including David Davis (1815-1886), an associate justice of the United States Supreme Court in 1862-1877, a member of the United States Senate in 1877-1883, and presidentpro temporeof the Senate in 1881-1883; Governor John M. Hamilton (1847-1905), Governor Joseph W. Fifer (b. 1840); and Adlai Ewing Stevenson (b. 1835), a Democratic representative in Congress in 1875-1877 and 1879-1881, and vice-president of the United States in 1893-1897. Bloomington’s prosperity increased after 1867, when coal was first successfully mined in the vicinity.
In theTransactionsof the Illinois State Historical Society for 1905 may be found a paper, “The Bloomington Convention of 1856 and Those Who Participated in it.”
In theTransactionsof the Illinois State Historical Society for 1905 may be found a paper, “The Bloomington Convention of 1856 and Those Who Participated in it.”
BLOOMINGTON,a city and the county-seat of Monroe county, Indiana, U.S.A., about 45 m. S. by W. of Indianapolis. Pop. (1890) 4018; (1900) 6460, including 396 negroes; (1910) 8838. It is served by the Chicago, Indianapolis & Louisville and the Indianapolis Southern (Illinois Central) railways. Bloomington is the seat of the Indiana University (co-educational since 1868), established as a state seminary in 1820, and as Indiana College in 1828, and chartered as the State university in 1838; in 1907-1908 it had 80 instructors, 2051 students, and a library of 65,000 volumes; its school of law was established in 1842, suspended in 1877 and re-established in 1889; its school of medicine was established in 1903; but most of the medical course is given in Indianapolis; a graduate school was organized in 1904; and a summer school (or summer term of eleven weeks) was firstheld in 1905. Dr David Starr Jordan was the first president of the university in 1885-1891, when it was thoroughly reorganized and its curriculum put on the basis of major subjects and departments. The university’s biological station is on Winona Lake, Kosciusko county. Among the manufactures of Bloomington are furniture and wooden ware. There are valuable limestone quarries in the vicinity. The city was first settled about 1818.
BLOOMSBURG,a town and the county-seat of Columbia county, Pennsylvania, U.S.A., on Fishing Creek, 2 m. from its confluence with the Susquehanna, and about 40 m. S.W. of Wilkes-Barre. Pop. (1890) 4635; (1900) 6170 (213 foreign-born); (1910) 7413. It is served by the Delaware, Lackawanna & Western, the Philadelphia & Reading, and the Bloomsburg & Sullivan and the Susquehanna, Bloomsburg & Berwick railways (the last two only 30 m. and 39 m. long respectively); and is connected with Berwick, Catawissa and Danville by electric lines. The town is built on a bluff commanding extensive views. Among the manufactures of Bloomsburg are railway cars, carriages, silk and woollen goods, furniture, carpets, wire-drawing machines and gun carriages. Iron ore was formerly obtained from the neighbouring hills. The town is the seat of a state normal school, established as such in 1869. Bloomsburg was laid out as a town in 1802, became the county-seat in 1846, and was incorporated in 1870.
BLOUNT, CHARLES(1654-1693), English author, was born at Upper Holloway on the 27th of April 1654. His father, Sir Henry Blount (1602-1682), was the author of aVoyage to the Levant, describing his own travels. He gave his son a careful education, and is said to have helped him in hisAnima Mundi; or An Historical Narration of the Opinions of the Antients concerning Man’s Soul after his Life, according to unenlightened Nature(1679), which gave great offence by the sceptical views expressed in it. It was suppressed by order of the bishop of London, and even burnt by some over-zealous official, but a re-issue was permitted. Blount was an admirer of Hobbes, and published his “Last Sayings” (1679), a pamphlet consisting of extracts fromThe Leviathan. Great is Diana of the Ephesians, or the Original of Idolatry, together with the Political Institution of the Gentiles’ Sacrifices(1680) attracted severe criticism on the ground that in deprecating the evils of priestcraft Blount was attacking Christianity itself. His best-known book,The Two First Books of Philostratus concerning the Life of Apollonius Tyaneus...(1680), is said to have been prohibited in 1693, chiefly on account of the notes, which are stated by Bayle (note,s.v. Apollonius) to have been taken mainly from a MS. of Lord Herbert of Cherbury. Blount contributed materially to the removal of the restrictions on the freedom of the press, with two pamphlets (1693) by “Philopatris,” mainly derived from Milton’sAreopagitica. He also laid a successful trap for the censor, Edmund Bohun. Under the name of “Junius Brutus” he wrote a pamphlet entitled “King William and Queen Mary Conquerors.” The title-page set forth the theory of the justice of title by conquest, which Blount knew to be agreeable to Bohun. It was duly licensed, but was ordered by the House of Commons to be burnt by the common hangman, as being diametrically opposed to the attitude of William’s government on the subject. These proceedings showed the futility of the censorship, and hastened its overthrow.
Blount had fallen in love with his deceased wife’s sister, and, in despair of overcoming her scruples as to the legality of such a marriage, shot himself in the head. He survived for some time, refusing help except from his sister-in-law. Alexander Pope asserted (Epilogue to the Satires, Note, i. 124) that he wounded himself in the arm, pretending to kill himself, and that the result was fatal contrary to his expectations. He died in August 1693.
Shortly before his death a collection of his pamphlets and private papers was printed with a preface by Charles Gildon, under the title of theOracles of Reason. HisMiscellaneous Works(1695) is a fuller edition by the same editor.
Shortly before his death a collection of his pamphlets and private papers was printed with a preface by Charles Gildon, under the title of theOracles of Reason. HisMiscellaneous Works(1695) is a fuller edition by the same editor.
BLOUNT(orBlunt),EDWARD(b. 1565?), the printer, in conjunction with Isaac Jaggard, ofMr William Shakespeares Comedies, Histories and Tragedies. Published according to the true Originall Copies(1623), usually known as the first folio of Shakespeare. It was produced under the direction of John Heming (d. 1630) and Henry Condell (d. 1627), both of whom had been Shakespeare’s colleagues at the Globe theatre, but as Blount combined the functions of printer and editor on other occasions, it is fair to conjecture that he to some extent edited the first folio. The Stationers’Registerstates that he was the son of Ralph Blount or Blunt, merchant tailor of London, and apprenticed himself in 1578 for ten years to William Ponsonby, a stationer. He became a freeman of the Stationers’ Company in 1588. Among the most important of his publications are Giovanni Florio’s Italian-English dictionary and his translation of Montaigne, Marlowe’sHero and Leander, and theSixe Court Comediesof John Lyly. He himself translatedArs Aulica, or the Courtier’s Arte(1607) from the Italian of Lorenzo Ducci, andChristian Policie(1632) from the Spanish of Juan de Santa Maria.
BLOUNT, THOMAS(1618-1679), English antiquarian, was the son of one Myles Blount, of Orleton in Herefordshire. He was born at Bordesley, Worcestershire. Few details of his life are known. It appears that he was called to the bar at the Inner Temple, but, being a zealous Roman Catholic, his religion interfered considerably with the practice of his profession. Retiring to his estate at Orleton, he devoted himself to the study of the law as an amateur, and also read widely in other branches of knowledge. He died at Orleton on the 26th of December 1679. His principal works areGlossographia; or, a dictionary interpreting the hard words of whatsoever language, now used in our refined English tongue(1656, reprinted in 1707), which went through several editions and remains most amusing and instructive reading;Nomolexicon: a law dictionary interpreting such difficult and, obscure words and terms as are found either in our common or statute, ancient or modern lawes(1670; third edition, with additions by W. Nelson, 1717); andFragmenta Antiquitatis: Ancient Tenures of land, and jocular customs of some mannors(1679; enlarged by J. Beckwith and republished, with additions by H.M. Beckwith, in 1815; again revised and enlarged by W.C. Hazlitt, 1874). Blount’sBoscobel(1651), giving an account of Charles II.’s preservation after Worcester, with the addition of the king’s own account dictated to Pepys, has been edited with a bibliography by C.G. Thomas (1894).
BLOUNT, SIR THOMAS POPE(1649-1697), English author, eldest son of Sir Henry Blount and brother of Charles Blount (q.v.), was born at Upper Holloway on the 12th of September 1649. He succeeded to the estate of Tittenhanger on his mother’s death in 1678, and in the following year was created a baronet. He represented the borough of St Albans in the two last parliaments of Charles II. and was knight of the shire from the revolution till his death. He married Jane, daughter of Sir Henry Caesar, by whom he had five sons and nine daughters. He died at Tittenhanger on the 30th of June 1697. HisCensura celebrorum authorum sive tractatus in quo varia virorum doctorum de clarissimis cujusque seculi scriptoribus judicia traduntur(1690) was originally compiled for Blount’s own use, and is a dictionary in chronological order of what various eminent writers have said about one another. This necessarily involved enormous labour in Blount’s time. It was published at Geneva in 1694 with all the quotations from modern languages translated into Latin, and again in 1710. His other works areA Natural History, containing many not common observations extracted out of the best modern writers(1693),De re poetica, or remarks upon Poetry, with Characters and Censures of the most considerable Poets....(1694), andEssays on Several Occasions(1692). It is on this last work that his claims to be regarded as an original writer rest. The essays deal with the perversion of learning, a comparison between the ancients and the moderns (to the advantage of the latter), the education of children, and kindred topics. In the third edition (1697) he added an eighth essay, on religion, in which he deprecated the multiplication of ceremonies. He displays throughout a hatred of pedantry and convention, which makes his book still interesting.