Chapter 2

"These are Thy marvellous works!"

"These are Thy marvellous works!"

"These are Thy marvellous works!"

and confess our total inability to fathom the unbounded.

If then no practical advantage can accrue from investigating the writings of the ancients on these subjects, beyond comparing their historical statements with those of more recent date, our purpose will be served by occasionally embodying any remarkable observations of the former with those of the latter.

In proceeding with this course it were better to confine our minds chiefly to two diseases which appear from history to have been known from the earliest periods, these are the Plague and the Small Pox, mentioning other diseases onlyen route.

Passing then, to the sixth century of the Christian era for the first distinct and connected account of the Plague, it appears from a host of testimony, that the history of this disease, as given by Procopius, well merits our attention. Drs. Friend and Hamilton, in their Histories of Medicine, and Gibbon, in his History of Rome, are equally warm in their praise of Procopius: the latter says, he "emulated the skill and diligence of Thucydides in thedescription of the Plague at Athens." The account given by Procopius of this disease, does not differ materially from that given by subsequent eye-witnesses of similar pestilences. Its point of origin is clearly marked, and its mode of dispersion in all directions distinctly traced from "the neighbourhood of Pelusium, between the Serbonian bog and the eastern channel of the Nile." It commenced in the year 542. It raged in Constantinople in the following year, and it was in this city that our historian gathered the materials which are handed down to us. When, however, we anxiously look for any explanation as to the cause of the malady, we are told that it must have been a direct visitation from Heaven, in consequence of the eccentric characters exhibited in its wide-spreading influence, in not yielding to the scrutiny nor bending to the laws known to prevail, and to regulate the course of other diseases: neither country nor clime, age nor sex, the strong and healthy, nor the weakly and previously diseased, could be said to be free from its indiscriminate destruction.

But some phenomena preceding the outbreak of the pestilence are observed as coincidences by all authors. Gibbon thus writes: "I shall conclude this chapter with the comets, the earthquakes, and the plague which astonished or afflicted the age of Justinian." From the accounts given by this author, earthquakes for some years had been threatening and destroying many portions of the globe,that in the ruins of cities and in the chasms of the earth, great was the sacrifice of human life. Constantinople, which suffered so severely from the plague is said to have been shaken for forty days. These great disturbances of the globe have been always looked upon as indicating other and important influences of a secret or hidden nature; these impressions on the minds of the people are traceable throughout the histories of all epidemics, and have been sufficiently distinct among the people of our own time, preceding and during the period of infliction.

From this short notice of the Plague of 543, I pass to the ninth century, when Rhazes, the Arabian physician, endeavoured to enlighten the world on the subject of Small Pox.[19]In quoting his opinions, I am not to be understood as subscribing to them, but merely endeavouring to point out some peculiar and interesting observations.

First, then, Rhazes attributes the disease to a condition of the blood, which he thus describes, to shew how it happens that in infancy and childhood the disease is most prevalent, and that old age isleast liable to the affection.[20]"The blood of infants and children may be compared tomust, in which the coction leading to perfect ripeness has not yet begun, nor the movement towards fermentation taken place; the blood of young men may be compared to must which has already fermented and made a hissing noise, and has thrown out abundant vapours and its superfluous parts, like wine which is now still and quiet, and arrived at its full strength, and as to the blood of old men, it may be compared to wine which has now lost its strength, and is beginning to grow vapid and sour."

"Now the Small Pox arises when the blood putrifies and ferments, so that the superfluous vapours are thrown out of it, and it is changed from the blood of infants which is like must, into the blood of young men which is like wine perfectly ripened: and the Small Pox itself may be compared to the fermentation and the hissing noise which take place at that time."

But the cause of the disease is simply alluded to by this author, as depending upon "occult dispositions in the air," and as he speaks here of Measles with the Small Pox he goes on to say—"which necessarily cause these diseases and predispose bodies to them." This notion of Rhazes that there is some peculiar condition of the blood which favours a process resembling fermentation is not without interest. The circumstance that individuals are notusually liable to a second attack of the disease, no doubt directed the attention of this physician to compare the process of fermentation with disease of such a nature, seeing that when the whole of the saccharine matter was converted into spirit, the hissing noise, as he calls it, or the disengagement of carbonic acid gas would cease, and the capacity for fermentation be entirely gone. So that the occult conditions of the air, their power of inducing a disease, and multiplying the matter capable of engendering a similar affection, stood in the mind of Rhazes as analogous if not identical phenomena.

We pass now without further comment to the epidemics of the Middle Ages; and here the work of the philosophical Hecker leaves us little else to desire in the way of information, as far as it is obtainable from published records. From the manner in which he has grouped the facts which presented themselves to his mind in the course of a most laborious research, he has saved the student of this subject much toil in acquiring matter for reflection; he has here but to read and digest.

I know not how to select from this invaluable work the most striking passages, to strengthen and support my hypothesis, for not a page is destitute of facts corroborative of the doctrine that vital germs are the material agents of pestilential disorders. The opening paragraph to the Black Death is a most cogent illustration of the assertion; it is, as it were, the theme of the work. "ThatOmnipotence, which has called the world with allits living creatures into one animated being, especially reveals himself in the desolation of great pestilences. The powers of creation come into violent collision; the sultry dryness of the atmosphere; the subterranean thunders; the mist of overflowing waters are the harbingers of destruction. Nature is not satisfied with the ordinary alternations of life and death, and the destroying angel waves over man and beast his flaming sword."

I must here apologise for large transcripts from Hecker's work, for neither could I command the amount of knowledge there displayed, nor use such appropriate language as the learned translator has employed.

It is not doubted that the Black Death was an Oriental plague, only of more than usual severity, and wider spread influence of the infectious nature of this disease, and the active properties of the matter producing it. Hecker says, "articles of this kind—bedding and clothes—removed from the access of air, not only retain the matter of contagion for an indefinite period,but also increase its activity, and engender it like a living being, frightful ill consequences followed for many years after the first fury of the pestilence was past."[21]

As extraordinary atmospheric and telluric phenomena preceded the Plague in the time of Justinian, so do we find similar instances recorded as the precursor of a similar visitation 700 years later. I am concerned more with those circumstances which refer more especially to my subject,viz.the development of organic matter, and the peculiar odours of the atmosphere, the latter being evidence of some foreign and unusual production in our respiratory media. "On the island of Cyprus, before the earthquake, a pestiferous wind spread so poisonous an odour, that many being overpowered by it, fell down suddenly and expired in dreadful agonies. A thick stinking mist advanced from the east, and spread itself over Italy."

It is probable that the atmosphere contained foreign and sensibly perceptible admixtures to a great extent, which, at least in the lower regions, could not be decomposed or rendered ineffective by separation. In 1348 an unexampled earthquake shook Greece, Italy, and the neighbouring countries. During this earthquake the wine in the casks became turbid, a proof that changes causing a decomposition of the atmosphere had taken place. "The insect tribe was wonderfully called into life, as if animated beings were destined to complete the destruction which astral and telluric powers had began."

"The corruption of the atmosphere came from the east, but the disease itself came not upon the wings of the wind, but was only excited and increased by the atmosphere where it had previously existed."

"The most powerful of all the springs of the disease was contagion; for in the most distant countries, which had scarcely yet heard the echo of the first concussion, the people fell a sacrifice to organic poison, the untimely offspring of vital energies thrown into violent commotion."

"After the cessation of the Black Plague, a greater fecundity in women was every where remarkable, a grand phenomena, which from its occurrence after every destructive pestilence, proves to conviction the prevalence of a higher power in the direction of general organic life."

In the article Contagion, of the Essay, Sweating Sickness: "Most fevers which are produced by general causes, propagate themselves for a time spontaneously." "The exhalations of the affected become the germs of a similar decomposition in those bodies which receive them, and produce in these a like attack upon the internal organs,and thus a merely morbid phenomenon of life, shows that it possesses the fundamental property of all life, that of propagating itself in an appropriate soil. On this point there is no doubt, the phenomena which prove it have been observed from time immemorial, in an endless variety of circumstances, but always with a uniform manifestation of a fundamental law."

Mead, in his Essay on the Plague, makes many observations of great interest and worthy a physician of eminence; and where, in recent times, shall we look for any more definite information concerning the causes of pestilences? It is not a little singular that at the time this book was published, it was read with such avidity that it went through seven editions in one year.[22]From this circumstance we may gather that the public generally took a lively and proper interest in a subject that was not only of domestic, but national importance. Whether this interest was stimulated by the fact that the work was written expressly by order of thegovernment, it is now impossible to say, at any rate much credit is due to the Lords of the Regency for having placed so important a duty upon one so thoroughly and in every way so duly qualified for the task as Dr. Mead. It had been well if some of the advice given at that time, as means of protection against the Plague, had been applied and put in force during the late visitation of epidemic Cholera, for, however the minds of some may be convinced of the non-contagiousness of Cholera, there are many who hold a different opinion, and all will acknowledge, that if not strictly a contagious affection, it is clearly proved to be capable of being carried from place to place, or to use Dr. Copland's words, it is "a portable disease." But this is not the place to discuss the subject of contagion, allusion will be made to it hereafter. To return, Mead's expressions are singularly illustrative of the vital power possessed by the germs of disease; he says, "There are instances of the distemper's being stopt by the winter cold, and yet the seeds of it not destroyed, but only kept unactive,till the warmth of the following spring has given them new life and force. His confession as to the hidden cause of the disease, is worthy transcribing: "We are acquainted too little with the laws, by which the small parts of matter act upon each other, to be able precisely to determine the qualities requisite to change animal juices into such acrimonious humours, or to explainhow all the distinguishing symptoms attending the disease are produced."[23]

On the spread of the Plague is the following:—"The plague is areal poison, which being bred in the southern parts of the world, maintains itself there by circulating from infected persons to goods, that when the constitution of the air happens to favour infection, it rages with great violence." Contagious matter is lodged in goods of a loose and soft texture, which being packed up, and carried into other countries, let out, when opened, the imprisoned seeds of contagion, and produce the disease whenever the air is disposed to give them force, "otherwise they may be dispersed without any considerable ill effects." Gibbon thus speaks of the above quoted work: "I have read with pleasure Mead's short but elegant Treatise concerning Pestilential Disorders;" many also might read it at the present day with infinite advantage. Mead most satisfactorily combats the opinions of the French physicians who maintained the non-contagiousness of the Plague. Experience proves beyond doubt, that certain conditions of atmosphere, ofwhich we are ignorant, favour the growth and increase of pestilences as they do of all vegetation.

Dr. Bancroft was of opinion that specific contagions are each and severally creatures of Divine Wisdom, as distinctly and designedly exerted for their production, as it was to create the several species of animals and vegetables around us.

The indigenous fever of Ireland, which has several times shewn itself in an epidemic form, appears to have been as fatal, as the Plague in the South of Europe. Its devastations have generally been associated or preceded by famine and general distress. Dr. Harty, writing in 1820, says that thrice within the last eighty years has the same fever appeared in its epidemic character. In the year 1741 Ireland lost 80,000 of her inhabitants from this cause. It is a maculated typhus, and considered to be a special product of the Emerald Isle. It has been shewn that fever began to exceed its ordinary rate in those places first where famine and want of employment were most severely felt,[24]and that in such places and under such circumstances, it was most prevalent and fatal. The physicians generally believed it to have been spontaneously produced and not to have been imported. In the last Famine Fever of Ireland, Liverpool and several other places suffered severely from theimportation of their Channel neighbours with the disease in some instances, and the infection in others about their persons. Hitherto these have to all appearance been the limits of the affection; we know not, however, how soon the time may come when the invisible bonds which have thus chained the disease to certain localities may be severed, and spreading itself like other pestilences in an aggravated form, attack this country as a last and crowning act of retributive justice. At present it has but cost us money and regrets, but if the history of pestilences is to be heeded, there are many tokens which seem to indicate that a few slight concurrent circumstances only are wanting, to bring the full force of this disease upon us; then will there be a sacrifice of life. Edinburgh and other towns of Scotland have had some visitations already, ourselves but slightly, but let our labouring population suffer to any large extent for want of work, and we shall inevitably be the sufferers from that fever which in consequence of general destitution is now always more or less prevalent in Ireland.

The Sweating Sickness prevailed in England alone at first, but at length sought foreign victims. The Cholera is an exotic disease, as well as the Plague, but they occasionally have visited our shores, and their seeds remain among us. The Small Pox is now even not known in some parts of the world, but when once it is established, who can predict the period of its first appearance in anepidemic form. The history of the disease informs us that in all the countries where it has been introduced, sooner or later an epidemic has seized the inhabitants.

A disease previously unknown in India appeared at Rangoon in the year 1824, which obtained the name of Scarlatina Rheumatica. Four years afterwards it attacked the Southern States of North America, and though the disease was so impartial as scarcely to spare a single individual of any town to which it extended its influence, it was not accompanied with that mortality which has usually been the characteristic of wide spread epidemics.

There is one peculiar feature of all epidemics which may be here mentioned as indicative of some definite, though at present unaccountable cause, operating in the sudden suppression of the disease after a certain period of duration. This distinctive character may almost be considered as a law in reference to these affections; if we take three distinct diseases, the Plague, the Irish Fever and the Cholera, we find the rule apply to all. Of the latter disease we have so recently been witnesses, that I need not quote authorities on this point concerning it. In Dr. Patrick Russell's work on the Plague at Aleppo I find the following remarkable passage. After alluding to the great increase of pestilential effluvia that there must be towards the close of an epidemic, compared with the amount at the onset of the disease, and expressing hisastonishment that so many escape infection, he says: "The fact, however unaccountable, is unquestionably certain; the distemper seems to be extinguished by some cause or causes equally unknown, as those which concurred to render it more or less epidemical in its advance and at its height." He then mentions that in Europe the sudden cessation may be partly attributable to the measures adopted for preventing its extension; but "at Aleppo, where the disease is left to run its natural course, and few or no means of purification are employed, it pursues nearly the same progress in different years; it declines and revives in certain seasons, and at length, without the interference of human aid, ceases entirely."

The expressions of Dr. Harty on this subject, in connexion with the Irish Fever, would apply as well to all other epidemics: "It is a fact, that though every diversity of management was resorted to for effecting the suppression of the disease, yet, nevertheless, there was an almost simultaneous and apparently spontaneous decline of the epidemic in the various and most remote parts of Ireland. It is not an easy matter to offer a satisfactory explanation of this circumstance,some general cause mustno doubt have influenced the subsidence of the disease, yet that cause could not be atmospheric, inasmuch as the decline, though it might be said to be simultaneous, was not sufficiently so to admit of that explanation."

SECTION III.

THE DISPERSION OF PLANTS AND DISEASES.

The dispersion of Diseases and the dispersion of Plants, exhibit analogies which might be little expected, on a superficial view of the enquiry.

We are led to believe, that the earth as a whole, was not covered with vegetation in a day, the geological history of this planet is one of development, and though at first sight this expression of opinion may appear to savour of doubt in the Mosaic record, a more extended acquaintance with the subject, favours rather and confirms Scripture history.

As the peopling of the earth has been a gradual process with the animal creation, so has it been also with the vegetable kingdom. We see at the present day, that plants by various means of transit from place to place, multiply themselves on new soils and in new climes, the same with animals. By other means we observe, or can trace, the extinction from various localities and countries, of members of both the animal and vegetable kingdom.

We learn that originally this planet had a temperature much higher than at present, and that the variation of temperature between the equator and the poles, which we now witness, did not obtain in the earlier condition of the globe. We are given to understand, and not without considerable proof,if not demonstration, that the earth was a vast bog, in which rank vegetation grew, and in which the ichthyosauri and plesiosauri, must have floundered about as unwieldy and loathsome bodies. We can readily conceive a condition of atmosphere at this time to have been loaded with pestiferous vapours of an organized nature; it is entirely in accordance with all we know, that it should have been so. Allied forms of plants to those now in existence, are found in the form of fossils, by which comparisons are made, but how the transition into the present Flora took place, or at what period, it is impossible to say. That these plants should have been entirely destroyed during the revolutions of the earth by earthquakes, and their consequences; the collection of waters into the vacuities formed, and their draining off from other places by elevations of the land, is not to be dwelt on without astonishment; then again the ultimate changes of temperature on the surface of the earth, may have been another element in the history of their extinction. But if we may be allowed to imagine that there were organic germs floating in the vapours of the atmosphere, these would hardly be subject to the same influences as those which depended solely on their fixation to the soil for subsistence. The atmosphere, their native element, being influenced by the commotions from below, would be agitated; vortiginous currents would be established, hurricanes would sweep over the stagnant pool and reeking morass,and the higher regions of the air might have thus given protection to these subtle germs, while almost a total extinction of the elegant ferns, the stately palm, and the towering cane was in course of procedure. Then when the strife of the earth and elements had subsided, these would descend with the gentle breezes, and again find in various spots a local habitation—

"Where blue mists, through the unmoving atmosphere,Scatter the seeds of pestilenceand feed unnatural vegetation."

"Where blue mists, through the unmoving atmosphere,Scatter the seeds of pestilenceand feed unnatural vegetation."

"Where blue mists, through the unmoving atmosphere,

Scatter the seeds of pestilenceand feed unnatural vegetation."

In the new era, when the earth took its present physiognomy, who shall say whether much of the pestiferous matter may not have been enclosed and condensed in the bowels of the earth, and when it is remembered, that earthquakes and convulsions of nature,[25]have invariably preceded the outbreak ofany great pestilences, that stinking mists, coming from some unknown regions, and unusual vegetations have made their appearance in concert at these times, what I ask is more natural than to imagine, that they have been let loose during the general convulsion? It may be asked, what is to be said about that revolution of the earth, when the great Deluge spread over the whole face of the globe? It can only be replied, that this is a part of the scheme of cosmogony into which we are not called upon to enter. There are yet strenuous supporters of the partial as well as total submersion of this planet, but whether it be true that the vast torrents which appear to have swept the surface uniformly in a southern direction, were of a date coeval with the deluge, and constituted an essential portion of the phenomena, of which one was, that "the fountains of the great deep were broken up," or whether they were anterior to this catastrophe, will not at all interfere with the conjecture of a very early formation and propagation of the germs of pestilential diseases, for the commotions of a deluge were less likely to interfere with the vapours of the atmosphere, than extensive volcanic and electric disturbances. Moreover, it is rather in favour of this theory, that theregions where the temperature and exhalations most nearly resemble those of the former condition of the earth, are those in which pestilential disorders most frequently arise, and where their virulence has always been most strongly marked.

After the various commotions which left the globe, with its present physiognomy of mountains, plains, valleys, rivers, lakes, and oceans; a new Flora and Fauna appeared to adorn and animate the scene of man's existence. Plants and animals were created apparently in adaptation to the numerous climes, which the seasons in the various latitudes or the elevations of the soil, were prepared to render fruitful and useful each in its own sphere. Besides this, the plants of the same latitude, in some instances, differ materially from each other; in this case it seems that the soil has much to do with this peculiarity, for it is certain that the soil and the contiguous atmosphere, have a close and intimate relation; the drought of the desert depends upon the sand, as humid atmosphere is connected with the morass. To illustrate the tendency which vegetation shews in appropriating one locality more than another, I may quote the following: "Some of the volcanic masses of the Æolian or Lipari Islands, that have existed beyond the reach of history, are still without a blade of verdure; while others in various parts, of little more than two hundred years date, bear spontaneous vegetation, and the same is seen on two lavas of Etna near each other, for the oneof 1536 is still black and arid, while that of 1636, is covered with oaks, fruit trees, and vines."

In comparing the diffusion of plants, and the diffusion of diseases, the different modes by which this generally has been effected may be considered under heads, that the comparison may be more readily traced.

First, seeds are diffused by the atmosphere, either by the prevalence of certain currents, which are produced by known laws, in which case, no difficulty occurs in the explanations; or in a more imperceptible manner, as by those more uncertain atmospheric currents of a partial nature, which, though they seem to have laws governing them, are not yet understood.

Second, seeds are transported by water across oceans, &c. when they can be floated on any material by which they are preserved, as by wrecks and masses of wood, which have been washed down the rivers.

Third, they are conveyed by man to all parts of the globe.

Fourth, a period of latency is observed to apply to them, that is, they require certain essential conditions before germination occurs; so that even in some localities, a plant may not have been known to exist in a particular neighbourhood, but by a train of circumstances, it may make its appearance, and again be a centre of development.

1st. I shall not here wander into the speculation,whether plants had originally one birth-place, as a centre from which they spread by various agencies, as supposed by Linnæus, nor into any enquiry beyond those facts, which may fairly come within our own comprehension, and within our own means of demonstration.

Many seeds are provided with means adapting them for floating in the atmosphere, these are by pappi, or winglets and hairs, but it cannot be doubted that the agency of atmospheric currents, is productive of considerable effects in the dispersion of lighter seeds, such as those of mosses, fungi, and lichens—lichens have been discovered in Brittany, which are peculiar to Jamaica, and Monsieur De Candolle concludes, that their seeds had been carried thence by the south-westerly winds, which prevail during a great part of the year on this portion of the French coast.

But Humboldt's testimony on the subject of winds is most satisfactory, for he says, "Small singing birds, and even butterflies, are found at sea, at great distances from the coast (as I have several times had opportunities of observing in the Pacific), being carried there by the force of the wind, when storms come off the land." It is generally believed, from abundance of proofs, that the trade winds, and other continuous currents, are means by which plants are conveyed from one country to another.[26]

As to the partial currents, Humboldt further says, "The heated crust of the earth occasions an ascending vertical current of air by which light bodies are borne upwards. M. Boussingault, and Don Mariano De Rivero, in ascending the summit of the Silla, one of the gneiss mountains of Caraccas, saw in the middle of the day, about noon, whitish shining bodies rise from the valley to the summit of the mountain, 5755 feet high, and then sink down towards the neighbouring sea coast. These movements continued uninterruptedly for the space of an hour. The whitish shining bodies proved to be small agglomerations of straws, or blades of grass, which were recognized by Professor Kunth, for a species of vilfa, a genus, which together with agrostis, is very abundant in the provinces of Caraccas and Cumana."

On the plague of locusts we read, that "the Lord brought an east wind upon the land, all that day and all that night, and when it was morning the east wind brought the locusts."

On the Black Death we read, "There were many locusts which had been blown into the sea by a hurricane, and a dense and awful fog was seen in the heavens, rising in the east, and descending upon Italy."

Of the Plague of 542, Gibbon says, "The winds might diffuse that subtle venom, but unless the atmosphere be previously disposed for its reception, the plague would soon expire in the cold ortemperate regions of the north. The disease alternately languished and revived, but it was not till a calamitous period of fifty-two years, that mankind recovered their health, or the air resumed its pure and salubrious quality."

In the history of the Sweating Sickness, of which there were five distinct visitations, we find ample allusions to the atmosphere, and the mode in which the disease was conveyed by this medium.

I quote again from Hecker: "It seemed thatthe banks of the Severnwere thefocus of the malady, and that from hence, a true impestation of the atmosphere, was diffused in every direction. Whithersoever the winds wafted the stinking mists, the inhabitants became infested with the sweating sickness.These poisonous clouds of mists were observed moving from place to place, with the disease in their train, affecting one town after another, and morning and evening spreading their nauseating insufferable stench. At greater distances, these clouds being dispersed by the wind, became gradually attenuated yet their dispersion set no bounds to the pestilence, and it was as if they had imparted to the lower strata of the atmosphere,a kind of ferment which went on engendering itself even without the presence of the thick misty vapour, and being received into men's lungs, produced the frightful disease everywhere."[27]

Mr. K. B. Martin, harbour-master of Ramsgate, in a communication to Lord Carlisle on the Cholera of last autumn, says, "At midnight of the 31st August (1849), the Samson (steam-tug) proceeded to the Goodwin Sands, where the crew were employed under the Trinity agent, assisting in work carried on there by that corporation. While there, at 3 A.M. 1st September,a hot humid haze, with a bog-like smell, passed over them; and the greater number of the men there employed instantly felt a nausea. They were in two parties. One man at work on the sand was obliged to be carried to the boat; and before they reached the steam vessel at anchor, the cramps and spasm had supervened upon the vomitings; but here they found two of the party on board similarly affected. Here then is a very marked case without any known predisposing local cause. Doubtless it was atmospheric, and in the hot blast of pestilence which passed over them."

Many more instances might be quoted, to shew that the germs of disease, as well as of plants, are borne on the wings of the wind from place to placein one country, and from one country to another, the distance being no obstacle, however great that may be.[28]"Dust and sands," says Sharon Turner, "heavier than many seeds, are borne by the winds and clouds for several hundred miles across the atmosphere, falling on the earth and seas as they pass along." "The clouds not only bring us occasionally meteoric stones, hail, andepidemics, but also vegetable seeds."[29]

2nd. The transportation of seeds of plants by water requires very little notice; every one is familiar with the mode in which coral islands, which gradually rise out of the sea, become covered with vegetation. "If new lands are formed, the organic forces are ever ready to cover the naked rock with life.—Lichens form the first covering of the barrenrocks, where afterwards lofty forest trees wave their airy summits. The successive growth of mosses, grasses, herbaceous plants and shrubs or bushes, occupies the intervening period of long but undetermined duration."

The following may be cited as an instance of the transportation of disease by water. "Cyprus lost almost all its inhabitants, and ships without crews were often seen in the Mediterranean, or afterwards in the North Sea, driving about,and spreading the plague wherever they went on shore."[30]

It requires no argument to enforce the conviction that cottons, woollens, furs, skins, &c. will retain the matter of infection for almost an indefinite period; instances of the kind have been already given; it is therefore easy to understand that portions of wrecks and ship's goods would be a frequent though unsuspected source of infection. Dr. Halley mentions a case, in which a bale of cotton was put on shore at Bermuda by stealth; it lay above a month without prejudice, where it was hid, but when opened and distributed among the inhabitants, it produced such a contagion that the living scarce sufficed to bury the dead. Dr. Walker found seeds dropt accidentally into the sea in the West Indies cast ashore on the Hebrides. He says, "the sea and rivers waft more seed than sails." The waters of many rivers induce diarrhœa and dysentery.[31]Well water also in manyplaces has a similar effect, especially if any surface drainage happens to find its way into the well.

3rd. The part performed by man himself in the communication of disease to his fellow creatures, is perhaps the most fruitful source of the extensive spread of epidemic and contagious diseases.

In the time of Moses, restrictions were laid on those who had the plague of the leprosy to avoid contagion; the dictum for one so affected was, "he shall dwell alone; without the camp shall his habitation be."[32]All the ancient authors believed in theinfectious nature of pestilential fevers, and some other diseases; but, according. to Mr. Adams, they held that no specific virus was the cause, and merely a contamination of the surrounding air by effluvia from the sick. Thucydides, Hippocrates, Procopius, Galen, Plutarch, all recognized the property of communicability from one individual to another of the plague; and Hecker, on the epidemics of the middle ages, abounds with instances in support of contagion. As regards small-pox and measles, Rhazes observes particularly the connection that exists between the condition of the air and the severity or mildness of these diseases, remarking that small-pox seldom happens to old men, except in pestilential, putrid, and malignant constitutions of the air in which this disease is usually prevalent.

The history of the introduction of Scarlet Fever, Hooping Cough, Lues, and other diseases into the various countries of the globe, is sufficiently convincing that men carry about with them the seeds of disease; that while these attach themselves to the persons and clothing of those who introduce them into new climes, and flourish independently of cultivation, yet the exotics which they foster with so much care, often disappoint their most sanguine expectations; and these "languishing in ourhothouses can give but a very faint idea of the majestic vegetation of the tropical zone." Art in this procedure fails to accomplish here, what nature but too sadly, under some circumstances, effects most readily. The germs of some diseases though of an exotic character, under congenial influences of various kinds, appear to flourish with native vigour: is it not so, also, with some forms of vegetation? The aloe, a native of Mexico, which lives, but does not thrive well, or reproduce under ordinary circumstances in this country, will occasionally send forth a most luxuriant blossom;[33]so rare is this, that some say it occurs every 50 or 100 years, but no law seems to be established on this point, any more than the statement that we may expect pestilential diseases at certain intervals. But that there are intervals ofuncertainduration when the aloe will blossom, when the grapes will ripen, and a general productiveness of exotics will occur, is as certain as that seasons will occur when contagion will be rife, and a most unusual multiplication of disease prevail. This is not an imaginary or speculative notion,—all observers of seasons and diseases within the last twenty years, may fully verify the statement.

In 1846, a large vine, the black Hambro-grape,ripened its fruit out of doors, and was as fine as any green-house production; but during nine years that the vine has been under my inspection, this was the only time I have witnessed such a result.

We are apt to attribute an abundant or scarce fruit season to temperature alone, but this is an error—for we have before remarked, that though certain lands may be in the same degree of latitude, the plants which thrive well on one land, will not do so on the other: in fine, that where reason and analogy would lead one to expect a particular form of vegetation, a totally different Flora is presented to the view. These facts are indeed suggestive of new and important deductions. Is it yet explained why the town of Birmingham should be free from Cholera? There is a large manufacturing population, a great number of poor, the usual overcrowding of individuals in small chambers, a considerable amount of destitution and depravity; irregular habits of living, and unwholesome diet, and doubtless many parts of the town, which on investigation would have yielded all the elements usually considered necessary for the localization of the disease: but no—here was some repelling cause, some opposing agent to the generation and propagation of the pestilential seeds. There are no known laws by which inorganic matter could be supposed to observe such a selection, or such an antagonism. Electricity, magnetism, ozone, gases, exhibit no such elective properties that here they will destroy, andthere they will spare; that they can almost depopulate small villages, and scarcely find a victim in Birmingham and Bath. But if we suppose a living, and multiplying matter as the cause of disease, many local causes may conspire to arrest the development of the germs, or perhaps, even utterly destroy them.

4th. As to the time of latency, facts crowd upon us indefinitely, as elements of comparison between vegetation generally, and disease in its early stages and history. The seeds of plants are extraordinarily tenacious of life. What a mysterious arrangement of the ultimate particles of matter must there be, by which the vital force remains apparently inactive for many years, and yet when the conditions arise favourable to its manifestation, as it were by an extraordinary fiat, life appears.

Previous to the year 1715, no broom grew in the King's Park, at Stirling; but in that year a camp was formed there, and the surface of the ground consequently was broken in many places. Wherever it was broken, broom sprang up. The plant was subsequently destroyed; but in 1745 a similar growth appeared after the ground had been again broken for a like purpose. Some time afterwards the park was ploughed up, and the broom became generally spread over it. "In several places in the neighbourhood of Edinburgh," says Professor Graham, "the breaking of the surface produces an abundant crop of Fumaria parviflora,although the same plant had never before been observed in the neighbourhood. It is impossible to say the lapse of time since these were buried, before they were again excited to the performance of all their vital functions." Dr. Graham also gives another proof of the vital force existing in seeds. "To the westward of Stirling there is a large peat bog, a great part of which has been flooded away by raising water from the River Teith, and discharging it into the Forth,—the under soil of clay being then cultivated. The clergyman of the parish standing by while the workmen were forming a ditch in this clay, which had been covered with fourteen feet of peat earth, saw some seeds in the clay which was thrown out of the ditch; he took some of them up and sowed them: they germinated and produced a crop of Chrysanthemum septum. What a period of years must have elapsed while the seeds were getting their covering of clay, and while this clay became buried under fourteen feet of peat earth!"[34]

What limit can there be to the dispersion of seeds when their vital properties may remain so long unimpaired? The seeds of which we have been speaking were, no doubt many of them, washed away with the waters of the Teith, and carried by the stream into the Forth; and who shall then mark their destination; for we have seen that by such means the most distant lands are supplied with vegetation; for whence come the plants which cover the Coral Islands, unless by the air and the water, and that both contribute, has been incontestably proved. Dr. Lindley states that melon seeds have been known to grow when forty-one years old; maize thirty years, rye forty years, the sensitive plant sixty years, kidney-beans a hundred years. But seeds in general have an indefinite period, apparently, at which they can retain their power of germination; for many of the seeds which had been kept in the herbarium of Tournefort for more than a century, were found to have preserved their fertility.

It has now to be shewn that the germs of disease also retain their vital powers in a state of dormancy during a lengthened period.

Mead has very judiciously observed, "to breed a distemper, and to give force to it when bred, are two different things." He further remarks, that the seeds of the Plague may confine themselves to a house or two during a hard frosty winter, and be preserved, and again put forth their malignant quality as soon as the warmth of the spring gives them force. It is certainly very remarkable that the Plague of London, which commenced at the latter end of the year 1664, should "lie asleep," as Mead says, from Christmas to the middle of February, and then break out in the same parish.

It has been also known that an infected bed laid by for seven years had done infinite mischief on being again brought into use. Indeed, it is quite uncertain for how long a period woollen, fur, linen, cotton, and other articles may retain infectious matter in a dormant state. It has been supposed by some that in closely packed bed and body clothes a multiplication of the germs may and does take place, nor do I see any reason why this should not be the case, for these articles contain within their structure the effluvia of the animal body, and they may possibly there find sufficient nutriment for their development. Nees von Esenbeck believed that some of the minute Cryptogamia were re-produced in the air, we are not therefore exceeding philosophical conjecture when we imagine a basis and substratum, though an unusual one, for the germs of vegetation. Exclusion from air and light,however, as would be the case in packed-up clothes, woulda priorigive a better colour to the conjecture, as these are the usual conditions necessary for the growth of seeds.

Small Pox and Cow Pox matter, which are now proved to be the same virus, the former modified by having been through a process of growth and maturation in the cow, are both remarkable for exhibiting their active properties after having lain dormant for a considerable time. And each, though so closely allied, retaining its specific properties.

This peculiarity in the history of Small Pox virus suggests a comparison with some phenomena of vegetation,viz.that of grafting or budding. The lower Cryptogamia in their fructifications resemble rather multiplication by buds than by seeds. M. Moyen's idea is that every spore or little globule, independently of its neighbouring one, lives, absorbs, assimilates, grows, and re-produces on its own account; this is certainly the characteristic of the Torula and the Uredo, and doubtless is so of many other of the Cryptogamia, the Protococcus nivalis is another instance. Other modes of cultivation produce also great varieties of results of an unexpected kind.

Would any one, says Dr. Walker, imagine that cabbage, cauliflower, savoy, kale, brocoli, and turnip-rooted cabbage, were the same species? yet nothing is more certain than that they are only varieties produced by the cultivation of the Brassica oleracea,a plant which grows wild on the sea-shores of Europe.

These varieties in vegetables have now become permanent, and though it is supposed that each is liable to return to its original condition, I am not yet certain that such is the tendency. A deterioration is not unlikely to ensue in the course of time, because the propagation by seeds must necessarily very much approach the system of intermarriage, on which Mr. Walker has so ably written and clearly shewn that as a result we may invariably expect a deterioration of the species. Dr. Darwin has also poetically described what his experience taught him.


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