1TablesAandBshow that the "expectation of life" for adults of forty years and over is shorter in New York City now than it was thirty years ago (Table A), and that this increase in the death-rate in the higher-age groups is manifested in recent years in a wide area in this country (Table B). This increased mortality is due chiefly to diseases of the heart, arteries, and kidneys, and to cancer.TABLE A[1a]Approximate Life Table, Trienna 1879-81 and 1909-11, Based on New York City StatisticsAgesExpectation of Life, 1879-81Expectation of Life, 1909-11Gain (+) or Loss (-) in Years of ExpectancyUnder 541.351.9+10.6546.351.1+ 4.81043.846.9+ 3.11539.742.5+ 2.82035.838.3+ 2.52532.634.3+ 1.73029.630.5+ 0.93526.726.9+ 0.24023.023.4- 0.54521.120.0- 1.15018.316.8- 1.55515.413.9- 1.56013.011.3- 1.76510.59.1- 1.4708.97.2- 1.7757.35.5- 1.8806.44.3- 2.1855.52.2- 3.3Balance+26.6-16.6+10.0TABLE B[1b]Comparison of Mortality of Males and Females, by Age Groups. Death-Rates per 1,000 Population (Registration States as Constituted in 1900)AgesMalesPercentage Increase or DecreaseFemalesPercentage Increase or Decrease1900191119001911Under 554.239.8-26.2745.833.3-27.295-94.73.4-27.664.63.1-32.6110-142.92.4-17.243.12.1-32.2615-194.93.7-24.494.83.3-31.2520-247.05.3-24.296.74.7-29.8525-348.36.7-19.288.26.0-26.8335-4410.810.4-3.709.88.3-15.3145-5415.816.1+1.9014.212.9-9.1555-6428.930.9+6.9225.826.8+0.7865-7459.661.6+3.3653.855.1+2.4275 and over146.1147.4+0.89139.5139.2+0.22All ages17.615.8-10.2316.514.0-15.151aMonthly Bull., Dept. of Health, City of New York, III (1913), 113.1bDublin,Amer. Jour. Public Health, III (1915), 1262.2General agreement respecting the true physiological and chemical nature of anaphylactic phenomena has not yet been reached. For a discussion of the theories of anaphylaxis, see in Hans Zinsser,Infection and Resistance(New York, 1914), chaps. xv-xviii; also Doerr, "Allergie und Anaphylaxis," in Kolle and Wassermann,Handbuch, 2d edition, 1913, II, 947.3Boston Med. and Surg. Jour., CLXVII (1912), 216.4Amer. Jour. Obstet.(New York), LXV (1912), 731.5F. B. Talbot,Boston Med. and Surg. Jour., CLXXV (1916), 409.6See, for example, Schloss,loc. cit.7Johns Hopkins Hosp. Bull., XXV (1914), 78.8See, for example, K. Koessler,Ill. Med. Jour., XXIII (1913), 66; Bronfenbrenner, Andrews, and Scott,Jour. Amer. Med. Assoc., LXIV (1915), 1306; F. B. Talbot,Boston Med. and Surg. Jour., CLXXI (1914), 708.9Jour. Amer. Med. Assoc., LXV (1915), 1837.10Strickler and Goldberg,Jour. Amer. Med. Assoc., LXVI (1916), 249.11Jour. Cutaneous Dis., XXXIV (1916), 70.12Amer. Jour. Dis. of Children, XI (1916), 441.13Science, XV (1902), 1016.14U.S. Dept. of Agric., Div. of Botany, Bull. 20, 1898.15Among the plants that seem to be most commonly implicated in the poisoning of stock are the larkspur (Delphinium.U.S. Dept. of Agric., Bull. 365, September 8, 1916), the water hemlock (Cicuta maculata) and others of the same genus, the lupines (U.S. Dept. of Agric., Bull. 405, 1916), some of the laurels (Kalmia), and the DeathCamasorZygadenus(U.S. Dept. of Agric., Bull. 125, 1915). The famous loco-weed of the western United States (U.S. Dept. of Agric., Bull. 112, 1909) is less certainly to be held responsible for all the ills ascribed to it (H. T. Marshall,Johns Hopkins Hosp. Bull., XXV [1914], 234).16Chesnut,U.S. Dept. of Agric., Div. of Botany, Bull. 20, 1898, p. 17.17Ibid., p. 28.18Ibid., p. 45. The seeds of the castor-oil bean, which contain a very powerful poison (ricin) allied to the bacterial toxins, have been known to cause the death of children who ate the seeds given them to play with.19Mayer,Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 12.20Cf. an instance of palmolin poisoning,Centralbl. f. Bakt., I, Ref., LXII (1914), 210.21Weekly Bull., N.Y. Dept. of Health, September 16, 1916.22Seventy-three species of mushrooms known or suspected to be poisonous are enumerated in a bulletin of the United States Department of Agriculture, Patterson and Charles ("Mushrooms and Other Common Fungi,"Bull. 175, 1915). This bulletin contains descriptions and excellent illustrations of many edible and of the commoner poisonous species.23Used in some places as a fly poison.24Ford,Science, XXX (1909), 97.25Another species of mushroom occurring in this country and commonly regarded as edible (Panaeolus papilionaceus) has on occasion shown marked intoxicating properties (A. E. Verrill,Science, XL (1914), 408).26Jour. Infect. Dis., III (1906), 191.27Jour. Amer. Med. Assoc., LXIV (1915), 1230.28W. W. Ford, "Plant Poisons and Their Antibodies,"Centralbl. f. Bakt., I Abt., Ref., LVIII (1913), 129 and 193, with full bibliography.29A. H. Clark,Science, XLI (1915), 795.30See W. M. Kerr,U.S. Nav., Monthly Bull., VI (1912), 401.31Ibid.32E. S. Reynolds,Lancet, I (1901), 166.33The sulphuric acid used in making glucose in the United States is authoritatively declared to be absolutely free from arsenic (report of hearing before Illinois State Food Standard Commission, June 21-23, 1916; seeAmer. Food Jour., July, 1916, p. 315).34E. W. Miller,Jour. Home Economics, VIII (1916), 361.35Phelps and Stevenson,Hyg. Lab., U.S. Public Health Service, Bull. 96, 1914, p. 55.36Harrington and Richardson,Manual of Practical Hygiene, 5th ed., p. 224.37See Alice Hamilton, "Hygiene of the Painters' Trade,"U.S. Bureau of Labor Statistics, Bull. 120, 1913.38In 1909 the value of foods canned in the United States amounted to about $300,000,000 (U.S. Dept. of Agric., Bull. 196, 1915).39W. D. Bigelow,Amer. Food Jour., XI (1916), 461.40Arch. f. Hyg., XLV (1902), 88;ibid., LXIII (1907), 67.41See, e.g., Harrington and Richardson,Practical Hygiene, 5th ed., p. 274.42Ztschr. f. Hyg., LXXV-LXXVI (1913-14), 55.43Bigelow,loc. cit.44A. W. Bitting,U.S. Dept. of Agric., Bull. 196, 1915.45U.S. Dept. of Agric., Report 97, 1913.46Folin,Preservatives and Other Chemicals in Foods(Harvard University Press, 1914), p. 32.47Folin,op. cit., p. 42.48SeeU.S. Dept. of Agric., Report 94, 1911.49Sawyer,Jour. Amer. Med. Assoc., LXIII (1914), 1537.50Eng. News, LXX (1913), 322.51Morse,Report of State Board of Health of Mass., 1899, p. 761.52R. H. Creel,Reprint from Public Health Reports, No. 72, Washington, 1912.53Health Bull. No. 76, Pennsylvania State Department of Health, December, 1915.54Amer. Jour. Public Health, II (1912), 321.55Institution Quarterly, III (1912), 18.56See also a similar instance reported by Lumsden,Hyg. Lab., U.S. Public Health and Marine Hosp. Service, Bull. 78, p. 165.57For a discussion of the oyster question see G. W. Fuller,Jour. of Franklin Institute, August, 1905;N.Y. City Dept. of Health, Monthly Bull., November, 1913, and May, 1915; H. S. Cumming,U.S. Public Health Service, Pub. Health Bull. 74, March, 1916.58Lancet, II (1895), 46.59Park and Krumwiede,Jour. Med. Research, N.S., XVIII (1910), 363.60Ztschr. f. Hyg., XXXV (1900), 265.61Centralbl. f. Bakt., I, Orig., LXVI (1912), 194.62Fleischvergiftungen u. Paratyphusinfektionen(Jena, 1910).63Rept. to Local Govt. Board, N.S. No. 77 (London, 1913).64Zeit. f. Hyg., XXII (1896), 53.65Brit. Med. Jour., I (1909), 1171.66Bernstein and Fish,Jour. Amer. Med. Assoc., LXVI (1916), 167.67Breslau aerztl. Ztschr., X (1888), 249.68Bernstein and Fish,Jour. Amer. Med. Assoc., LXVI (1916), 167.69Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 58-59.70Op. cit., pp. 60-62.71Jour. Infect. Dis., XX (1917), 457.72Centralbl. f. Bakt., I Orig., LIII (1910), 377.73Cor.-Bl. f. schweiz. Aerzte, XLII (1912), 281 and 332.74Jour. Hyg., XII (1912), 1.75See Sobernheim and Seligmann,Centralbl. f. Bakt., Ref., Beilage, L (1911), 134.76Report Med. Officer of Health(Newcastle-upon-Tyne, 1913).77Compiled from Savage,Report of Local Gov't Board, 1913.78Mayer,Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 8.79It must be noted that origin of the food from a diseased animal was not definitely proved in all the cases cited. Some of these cases should possibly be classed under human contamination (2).80Although not directly connected with the question of food poisoning, it is of interest to note that certain diseases of birds have been traced to infection with members of this group of bacteria. In a few cases, as in several epidemics among parrots in Paris and elsewhere, the infection has been communicated to man by contact.81Jour. Infect. Dis., XIX (1916), 700.82R. Trommsdorff, L. Rajchman, and A. E. Porter,Jour. Hyg., XI (1911), 89.83Hygiea, LXXV (1913), 1.84Progrès méd., 3d series, XXVI (1910), 25.85Ledingham and Arkwright,The Carrier Problem in Infectious Diseases, pp. 152-53.86Jour. Hyg., XI (1911), 24.87Münch. med. Wchnschr., LIV (1907), 979.88See, for example, H. Langer and Thomann,Deutsche med. Wchnschr., XL (1914), 493.89Ztschr. f. Infektionsk. ... d. Haustiere, VIII (1910), 237.90The consumption of raw sausage made with pig meat is particularly likely to give rise to trichiniasis.91Jour. Med. Research, VI (1901), 64.92Edelmann, Mohler, and Eichhorn,Meat Hygiene, 1916, p. 182.93Jour. Amer. Med. Assoc., LXVII (1916), 1908.94Brit. Med. Jour., II (1916), 139.95Another species ofClaviceps(C. paspali) which attacks the seeds of a wild grass is believed to be responsible for certain outbreaks of poisoning among cattle and horses (Science, XLIII [1916], 894).96Barger (Jour. Chem. Soc., XCV [1909], 1123) has shown that parahydroxyphenylethylamine is present in ergot and is in some degree responsible for the physiological action of the drug.97Although some of the early outbreaks were traced to the use of sausage, particularly in Württemberg, the proportion of recent botulism poisoning attributed to this food is no greater than of sausage-conveyed infections with the paratyphoid bacillus (chap. vi), and a number of the most completely studied outbreaks of botulism have been traced to ham, beans, and other foods.98Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 8.99E. Sacquépée,Progrès méd., XXVI (1910), 583.100Report to Local Govt. Board on Bacterial Food Poisoning and Food Inspection, N.S. No. 77, 1913, p. 27.101Southern Cal. Pract., XXII (1907), 370.102Ibid., XXV (1910), 121.103Arch. of Int. Med., XIV (1914), 589.104Amer. Med., X (1915), 85.105Jour. Amer. Med. Assoc., LXI (1913), 2301.106Loc. cit.107Loc. cit.108In the feces of a healthy pig (Kempner and Pollock,Deutsche med. Wchnschr., XXIII [1897], 505).109B. botulinusdoes not develop in media containing over 6 per cent of salt and should not be able to grow in meat properly covered in brine made with 10 per cent of salt (Römer,Centralbl. f. Bakt., XXVII [1900], 857).110G. Landmann,Hyg. Rundschau, XIV (1904), 449.111Wilbur and Ophüls,Arch. of Int. Med., XIV (1914), 589.112Phil. Jour. of Science, IX (1914), B6, p. 515.113K. Blunt and C. C. Wang,Jour. Biol. Chem., XXVIII (1916), 125.114Jordan and Harris,Jour. Infect. Dis., VI (1909), 401.115Ibid.116E. B. Vedder,Jour. Amer. Med. Assoc., LXVII (1916), 1494.117McCollum and Davis,Jour. Biol. Chem., XXIII (1915), 181.118Goldberger,Jour. Amer. Med. Assoc., LXVI (1916), 471.119MacNeal,Jour. Amer. Med. Assoc., LXVI (1916), 975; Jobling,Jour. Infect. Dis., XVIII (1916), 501.120Gasbarrini,Policlinico, November 14, 1915; abstract,Jour. Amer. Med. Assoc., LXV (1915), 2264.121Holst and Frölich,Jour. Hyg., VII (1907), 619; Moore and Jackson,Jour. Amer. Med. Assoc., LXVII (1916), 1931.122Jackson and Moody,Jour. Infect. Dis., XIX (1916), 511.
1TablesAandBshow that the "expectation of life" for adults of forty years and over is shorter in New York City now than it was thirty years ago (Table A), and that this increase in the death-rate in the higher-age groups is manifested in recent years in a wide area in this country (Table B). This increased mortality is due chiefly to diseases of the heart, arteries, and kidneys, and to cancer.
TABLE A[1a]
Approximate Life Table, Trienna 1879-81 and 1909-11, Based on New York City Statistics
TABLE B[1b]
Comparison of Mortality of Males and Females, by Age Groups. Death-Rates per 1,000 Population (Registration States as Constituted in 1900)
1aMonthly Bull., Dept. of Health, City of New York, III (1913), 113.
1bDublin,Amer. Jour. Public Health, III (1915), 1262.
2General agreement respecting the true physiological and chemical nature of anaphylactic phenomena has not yet been reached. For a discussion of the theories of anaphylaxis, see in Hans Zinsser,Infection and Resistance(New York, 1914), chaps. xv-xviii; also Doerr, "Allergie und Anaphylaxis," in Kolle and Wassermann,Handbuch, 2d edition, 1913, II, 947.
3Boston Med. and Surg. Jour., CLXVII (1912), 216.
4Amer. Jour. Obstet.(New York), LXV (1912), 731.
5F. B. Talbot,Boston Med. and Surg. Jour., CLXXV (1916), 409.
6See, for example, Schloss,loc. cit.
7Johns Hopkins Hosp. Bull., XXV (1914), 78.
8See, for example, K. Koessler,Ill. Med. Jour., XXIII (1913), 66; Bronfenbrenner, Andrews, and Scott,Jour. Amer. Med. Assoc., LXIV (1915), 1306; F. B. Talbot,Boston Med. and Surg. Jour., CLXXI (1914), 708.
9Jour. Amer. Med. Assoc., LXV (1915), 1837.
10Strickler and Goldberg,Jour. Amer. Med. Assoc., LXVI (1916), 249.
11Jour. Cutaneous Dis., XXXIV (1916), 70.
12Amer. Jour. Dis. of Children, XI (1916), 441.
13Science, XV (1902), 1016.
14U.S. Dept. of Agric., Div. of Botany, Bull. 20, 1898.
15Among the plants that seem to be most commonly implicated in the poisoning of stock are the larkspur (Delphinium.U.S. Dept. of Agric., Bull. 365, September 8, 1916), the water hemlock (Cicuta maculata) and others of the same genus, the lupines (U.S. Dept. of Agric., Bull. 405, 1916), some of the laurels (Kalmia), and the DeathCamasorZygadenus(U.S. Dept. of Agric., Bull. 125, 1915). The famous loco-weed of the western United States (U.S. Dept. of Agric., Bull. 112, 1909) is less certainly to be held responsible for all the ills ascribed to it (H. T. Marshall,Johns Hopkins Hosp. Bull., XXV [1914], 234).
16Chesnut,U.S. Dept. of Agric., Div. of Botany, Bull. 20, 1898, p. 17.
17Ibid., p. 28.
18Ibid., p. 45. The seeds of the castor-oil bean, which contain a very powerful poison (ricin) allied to the bacterial toxins, have been known to cause the death of children who ate the seeds given them to play with.
19Mayer,Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 12.
20Cf. an instance of palmolin poisoning,Centralbl. f. Bakt., I, Ref., LXII (1914), 210.
21Weekly Bull., N.Y. Dept. of Health, September 16, 1916.
22Seventy-three species of mushrooms known or suspected to be poisonous are enumerated in a bulletin of the United States Department of Agriculture, Patterson and Charles ("Mushrooms and Other Common Fungi,"Bull. 175, 1915). This bulletin contains descriptions and excellent illustrations of many edible and of the commoner poisonous species.
23Used in some places as a fly poison.
24Ford,Science, XXX (1909), 97.
25Another species of mushroom occurring in this country and commonly regarded as edible (Panaeolus papilionaceus) has on occasion shown marked intoxicating properties (A. E. Verrill,Science, XL (1914), 408).
26Jour. Infect. Dis., III (1906), 191.
27Jour. Amer. Med. Assoc., LXIV (1915), 1230.
28W. W. Ford, "Plant Poisons and Their Antibodies,"Centralbl. f. Bakt., I Abt., Ref., LVIII (1913), 129 and 193, with full bibliography.
29A. H. Clark,Science, XLI (1915), 795.
30See W. M. Kerr,U.S. Nav., Monthly Bull., VI (1912), 401.
31Ibid.
32E. S. Reynolds,Lancet, I (1901), 166.
33The sulphuric acid used in making glucose in the United States is authoritatively declared to be absolutely free from arsenic (report of hearing before Illinois State Food Standard Commission, June 21-23, 1916; seeAmer. Food Jour., July, 1916, p. 315).
34E. W. Miller,Jour. Home Economics, VIII (1916), 361.
35Phelps and Stevenson,Hyg. Lab., U.S. Public Health Service, Bull. 96, 1914, p. 55.
36Harrington and Richardson,Manual of Practical Hygiene, 5th ed., p. 224.
37See Alice Hamilton, "Hygiene of the Painters' Trade,"U.S. Bureau of Labor Statistics, Bull. 120, 1913.
38In 1909 the value of foods canned in the United States amounted to about $300,000,000 (U.S. Dept. of Agric., Bull. 196, 1915).
39W. D. Bigelow,Amer. Food Jour., XI (1916), 461.
40Arch. f. Hyg., XLV (1902), 88;ibid., LXIII (1907), 67.
41See, e.g., Harrington and Richardson,Practical Hygiene, 5th ed., p. 274.
42Ztschr. f. Hyg., LXXV-LXXVI (1913-14), 55.
43Bigelow,loc. cit.
44A. W. Bitting,U.S. Dept. of Agric., Bull. 196, 1915.
45U.S. Dept. of Agric., Report 97, 1913.
46Folin,Preservatives and Other Chemicals in Foods(Harvard University Press, 1914), p. 32.
47Folin,op. cit., p. 42.
48SeeU.S. Dept. of Agric., Report 94, 1911.
49Sawyer,Jour. Amer. Med. Assoc., LXIII (1914), 1537.
50Eng. News, LXX (1913), 322.
51Morse,Report of State Board of Health of Mass., 1899, p. 761.
52R. H. Creel,Reprint from Public Health Reports, No. 72, Washington, 1912.
53Health Bull. No. 76, Pennsylvania State Department of Health, December, 1915.
54Amer. Jour. Public Health, II (1912), 321.
55Institution Quarterly, III (1912), 18.
56See also a similar instance reported by Lumsden,Hyg. Lab., U.S. Public Health and Marine Hosp. Service, Bull. 78, p. 165.
57For a discussion of the oyster question see G. W. Fuller,Jour. of Franklin Institute, August, 1905;N.Y. City Dept. of Health, Monthly Bull., November, 1913, and May, 1915; H. S. Cumming,U.S. Public Health Service, Pub. Health Bull. 74, March, 1916.
58Lancet, II (1895), 46.
59Park and Krumwiede,Jour. Med. Research, N.S., XVIII (1910), 363.
60Ztschr. f. Hyg., XXXV (1900), 265.
61Centralbl. f. Bakt., I, Orig., LXVI (1912), 194.
62Fleischvergiftungen u. Paratyphusinfektionen(Jena, 1910).
63Rept. to Local Govt. Board, N.S. No. 77 (London, 1913).
64Zeit. f. Hyg., XXII (1896), 53.
65Brit. Med. Jour., I (1909), 1171.
66Bernstein and Fish,Jour. Amer. Med. Assoc., LXVI (1916), 167.
67Breslau aerztl. Ztschr., X (1888), 249.
68Bernstein and Fish,Jour. Amer. Med. Assoc., LXVI (1916), 167.
69Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 58-59.
70Op. cit., pp. 60-62.
71Jour. Infect. Dis., XX (1917), 457.
72Centralbl. f. Bakt., I Orig., LIII (1910), 377.
73Cor.-Bl. f. schweiz. Aerzte, XLII (1912), 281 and 332.
74Jour. Hyg., XII (1912), 1.
75See Sobernheim and Seligmann,Centralbl. f. Bakt., Ref., Beilage, L (1911), 134.
76Report Med. Officer of Health(Newcastle-upon-Tyne, 1913).
77Compiled from Savage,Report of Local Gov't Board, 1913.
78Mayer,Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 8.
79It must be noted that origin of the food from a diseased animal was not definitely proved in all the cases cited. Some of these cases should possibly be classed under human contamination (2).
80Although not directly connected with the question of food poisoning, it is of interest to note that certain diseases of birds have been traced to infection with members of this group of bacteria. In a few cases, as in several epidemics among parrots in Paris and elsewhere, the infection has been communicated to man by contact.
81Jour. Infect. Dis., XIX (1916), 700.
82R. Trommsdorff, L. Rajchman, and A. E. Porter,Jour. Hyg., XI (1911), 89.
83Hygiea, LXXV (1913), 1.
84Progrès méd., 3d series, XXVI (1910), 25.
85Ledingham and Arkwright,The Carrier Problem in Infectious Diseases, pp. 152-53.
86Jour. Hyg., XI (1911), 24.
87Münch. med. Wchnschr., LIV (1907), 979.
88See, for example, H. Langer and Thomann,Deutsche med. Wchnschr., XL (1914), 493.
89Ztschr. f. Infektionsk. ... d. Haustiere, VIII (1910), 237.
90The consumption of raw sausage made with pig meat is particularly likely to give rise to trichiniasis.
91Jour. Med. Research, VI (1901), 64.
92Edelmann, Mohler, and Eichhorn,Meat Hygiene, 1916, p. 182.
93Jour. Amer. Med. Assoc., LXVII (1916), 1908.
94Brit. Med. Jour., II (1916), 139.
95Another species ofClaviceps(C. paspali) which attacks the seeds of a wild grass is believed to be responsible for certain outbreaks of poisoning among cattle and horses (Science, XLIII [1916], 894).
96Barger (Jour. Chem. Soc., XCV [1909], 1123) has shown that parahydroxyphenylethylamine is present in ergot and is in some degree responsible for the physiological action of the drug.
97Although some of the early outbreaks were traced to the use of sausage, particularly in Württemberg, the proportion of recent botulism poisoning attributed to this food is no greater than of sausage-conveyed infections with the paratyphoid bacillus (chap. vi), and a number of the most completely studied outbreaks of botulism have been traced to ham, beans, and other foods.
98Deutsche Viertelj. f. öffentl. Ges., XLV (1913), 8.
99E. Sacquépée,Progrès méd., XXVI (1910), 583.
100Report to Local Govt. Board on Bacterial Food Poisoning and Food Inspection, N.S. No. 77, 1913, p. 27.
101Southern Cal. Pract., XXII (1907), 370.
102Ibid., XXV (1910), 121.
103Arch. of Int. Med., XIV (1914), 589.
104Amer. Med., X (1915), 85.
105Jour. Amer. Med. Assoc., LXI (1913), 2301.
106Loc. cit.
107Loc. cit.
108In the feces of a healthy pig (Kempner and Pollock,Deutsche med. Wchnschr., XXIII [1897], 505).
109B. botulinusdoes not develop in media containing over 6 per cent of salt and should not be able to grow in meat properly covered in brine made with 10 per cent of salt (Römer,Centralbl. f. Bakt., XXVII [1900], 857).
110G. Landmann,Hyg. Rundschau, XIV (1904), 449.
111Wilbur and Ophüls,Arch. of Int. Med., XIV (1914), 589.
112Phil. Jour. of Science, IX (1914), B6, p. 515.
113K. Blunt and C. C. Wang,Jour. Biol. Chem., XXVIII (1916), 125.
114Jordan and Harris,Jour. Infect. Dis., VI (1909), 401.
115Ibid.
116E. B. Vedder,Jour. Amer. Med. Assoc., LXVII (1916), 1494.
117McCollum and Davis,Jour. Biol. Chem., XXIII (1915), 181.
118Goldberger,Jour. Amer. Med. Assoc., LXVI (1916), 471.
119MacNeal,Jour. Amer. Med. Assoc., LXVI (1916), 975; Jobling,Jour. Infect. Dis., XVIII (1916), 501.
120Gasbarrini,Policlinico, November 14, 1915; abstract,Jour. Amer. Med. Assoc., LXV (1915), 2264.
121Holst and Frölich,Jour. Hyg., VII (1907), 619; Moore and Jackson,Jour. Amer. Med. Assoc., LXVII (1916), 1931.
122Jackson and Moody,Jour. Infect. Dis., XIX (1916), 511.
Transcriber's Notes:Illustrations have been moved from the middle of a paragraph to the closest paragraph break. Missing page numbers are connected to blank pages and moved illustrations. The following illustrations have been moved to other pages:Fig. 1was moved from page 15 to page16Fig. 3was moved from page 19 to page18Fig. 4was moved from page 23 to page22Fig. 5was moved from page 49 to page48Fig. 10was moved from page 87 to page88The punctuation in the index was inconsistent, all semi-colons in listings for page numbers have been changed into commas, they are not specially mentioned/marked in the list of changes. Subentries are in general separated by semi-colons, these have been added or changed from other punctuation marks silently. Sub-subentries are in general separated by commas, these have been added or changed from other punctuation marks silently.Atropin and atropine have been retained in both versions in this project.TableAin footnote1contains a potential mathematical error, the 2nd column (Expectation of Life 1879-81), row (Ages) 40 shows the value 23.0, it should be 23.9 to add up correctly in the 4th column (Gain or Loss). The original value (23.0) has been retained.Footnote2"also Doerr, "Allergie und Anaphylaxis," in Kolle" is cited often as "also Doerr, "Allergie und Anaphylaxie," in Kolle". It has been retained in the version printed in the book for authenticity reasons.Margarin (pages16and112) is in general spelled margarine, it has been retained in this book for reasons of authenticity.Maratti-oil (pages16and112) is in general known as moratti-oil, it has been retained in this book for reasons of authenticity.Hydrocarpus (pages16and111) is in general known as Hydnocarpus, it has been retained in this book for reasons of authenticity.Amanita caesaria (pages18,20, and109) is also known as Amanita caesarea but retained for this project in the first form.Muscarin (pages20,21,22, and112) is in general spelled muscarine, it has been retained in this book for reasons of authenticity.Zygadenus (pages25and115) is in general known as Zigadenus, it has been retained in this book for reasons of authenticity.The typhoid carrier in New York Mary Mallon (aka Typhoid Mary) mentioned on page45as well as on page112is spelled in this book as Mary Malloy, the original of the book has been retained.Other than the corrections listed below, printer's inconsistencies in spelling, punctuation, hyphenation, and ligature usage have been retained.The following misprints have been corrected:added 0 to +.89 in tableBfootnote1, second to last value in 4th column.changed "la face vulteuse" into "la face vultueuse" page21changed "Paneolus papilionaceus" into "Panaeolus papilionaceus" page21the italian mark-up for "XLV" in "f. öffentl. Ges., XLV" has been removed, footnote69changed "R. Trommsdorff, L. Rajchmann, and A. E. Porter," into "R. Trommsdorff, L. Rajchman, and A. E. Porter," footnote82changed "Paneolus papilionaceus" into "Panaeolus papilionaceus" page113
Transcriber's Notes:
Illustrations have been moved from the middle of a paragraph to the closest paragraph break. Missing page numbers are connected to blank pages and moved illustrations. The following illustrations have been moved to other pages:
The punctuation in the index was inconsistent, all semi-colons in listings for page numbers have been changed into commas, they are not specially mentioned/marked in the list of changes. Subentries are in general separated by semi-colons, these have been added or changed from other punctuation marks silently. Sub-subentries are in general separated by commas, these have been added or changed from other punctuation marks silently.
Atropin and atropine have been retained in both versions in this project.
TableAin footnote1contains a potential mathematical error, the 2nd column (Expectation of Life 1879-81), row (Ages) 40 shows the value 23.0, it should be 23.9 to add up correctly in the 4th column (Gain or Loss). The original value (23.0) has been retained.
Footnote2"also Doerr, "Allergie und Anaphylaxis," in Kolle" is cited often as "also Doerr, "Allergie und Anaphylaxie," in Kolle". It has been retained in the version printed in the book for authenticity reasons.
Margarin (pages16and112) is in general spelled margarine, it has been retained in this book for reasons of authenticity.
Maratti-oil (pages16and112) is in general known as moratti-oil, it has been retained in this book for reasons of authenticity.
Hydrocarpus (pages16and111) is in general known as Hydnocarpus, it has been retained in this book for reasons of authenticity.
Amanita caesaria (pages18,20, and109) is also known as Amanita caesarea but retained for this project in the first form.
Muscarin (pages20,21,22, and112) is in general spelled muscarine, it has been retained in this book for reasons of authenticity.
Zygadenus (pages25and115) is in general known as Zigadenus, it has been retained in this book for reasons of authenticity.
The typhoid carrier in New York Mary Mallon (aka Typhoid Mary) mentioned on page45as well as on page112is spelled in this book as Mary Malloy, the original of the book has been retained.
Other than the corrections listed below, printer's inconsistencies in spelling, punctuation, hyphenation, and ligature usage have been retained.
The following misprints have been corrected: