Dionin, C17H17NO(OH) (OC2H5HCl) + H2O = (C19H21O3ClN + H2O), the hydrochloride of the ethyl ester of morphine.
Actions and Uses.—It is claimed that this compound acts like morphine without producing constipation, nausea or lassitude. It is the conclusion of some good observers that it possesses no advantage over codeine. Applied to the eye, it causes a local vasodilation, leading to acute conjunctival edema. Dionin is recommended to relieve pain, especially in respiratory affections, as an antispasmodic in whooping-cough, for insomnia and externally in the treatment of corneal affections, conjunctivitis, iritis, etc. Dosage.—0·015 to 0·06 gramme (¼ to 1 grain). Externally it is applied in 10 to 20 per cent. solutions. Manufactured by E. Merck, Darmstadt. (Merck & Co., New York.)