Chapter VI — Description of the Skeleton — Diseases of the Nervous System

Nux vomica

,

another

medicine much used, and most important in the treatment of all nervous affections, is particularly noxious to dogs even in small quantities; a dose sufficient for a human subject under some circumstances, would almost inevitably destroy the animal under the same or analogous conditions.

A drachm of the powdered nux vomica is sufficient to destroy the largest and most powerful dog, while a few grains will sometimes produce death in a few minutes if administered to smaller animals.

We prescribed forty grains in a roll of butter for a worthless cur a short time since, which, as expected, produced great anxiety, difficulty of respiration, severe vomiting, tremors, spasmodic twitchings of the muscles, convulsions, and ultimate death in the course of half an hour. This powerful drug acts by causing a spasmodic stricture of the muscles engaged in respiration, as no signs of inflammation are observable in the stomach and other organs after death.

Spirits of turpentine

,

another

remedy both simple and innocent in its operations upon the human economy, and so frequently prescribed for the expulsion of worms from the bowels, is a dangerous medicine for a dog, and will often in very small quantities prove fatal.

Aloes

, a medicine more extensively used in canine pathology than any other in the

materia medica,

is also very peculiar in its operations upon these animals, they being able to bear immense doses of it, in fact quite sufficient to produce death if given to a hearty man.

Thus we might continue to enumerate other drugs which we have ascertained, from practical observation as well as the experiments of other, to exercise a peculiar action on the vital functions of the whole canine race, quite at variance with that common to both man and the other domestic animals.

In combating with the diseases of animals, the veterinary surgeon has more to contend with than the regular physician, and, in fact, should possess a knowledge and habit of observation even superior to the former; although the responsibility of his calling, in a moral sense, is much inferior to that of the other, as the importance of animal existence, under no circumstances, can be placed in comparison with that of human life: still acuteness of observation alone can direct him to the main cause of suffering in the brute creation, as the animal, though groaning under the most severe pains, cannot by any word of explanation point out to us the seat, the probable cause, or peculiar characteristics of such pain. We see that our dog is ill, he refuses his food, retires gloomily to his house, looks sullen, breathes heavy, is no longer delighted at our call. We cannot question him as to his feelings, or ask him to point out the particular region of his sufferings; we watch his motions, study his actions, and rely for our diagnosis upon general symptoms deduced from close observation.

Besides these external ocular evidences of morbid action, we have, as in the human subject, guides to direct us in forming a just opinion as to the nature of a dog's indisposition.

The

state of the

circulation

is the first thing that should command our particular attention.

The pulse of dogs in health varies from

one hundred to one hundred and twenty strokes per minute,

according to the size and peculiar temperament of the animal, being more frequent in the small breeds.

The standard of the setter, pointer, hound, &c., may be stated at one hundred and five.

The action of the heart may be felt by placing the hand immediately over that organ, or applying the fingers to several points in the body and limbs where the large arteries are somewhat superficial, as on the inside of the fore-knee and the thigh of the hind-leg.

If the pulse in a state of rest exceeds the average standard in frequency, regularity, and softness, and a general feeling of uneasiness be present, together with reddened eyes, warm nose, and coated tongue, we know at once that there is an unnatural derangement of the vital functions, and that

fever

in some form is present. The next question to determine is, upon what does this fever depend? whether it be idiopathic, arising from morbific causes difficult to define, or whether it be sympathetic, with some organic affection yet to be discovered.

The appearance of the

tongue

in canine diseases will often materially assist us in forming a correct diagnosis; this organ in simple fever loses its rose-colour and becomes pale and coated, the gums and fæces also participate in this change.

If, however, the tongue be much furred, with a bright inflammatory appearance around the edges, with high arterial excitement, and disgust of food, with general anxiety and craving for water in small but frequent quantities,

inflammation of the stomach or bowels

may be suspected. If, on the other hand, the tongue remains brown and streaked, with less action of the pulse, variable appetite and diminution of pain, derangement of the

liver

may be apprehended.

If, in connection with some or all of the above symptoms, the

breathing

be laboured and painful, with a disposition to remain in the erect or sitting position, with great anxiety and general distress, we must look to the

pulmonic viscera

as the seat of the disease.

Thus, by examining each and every individual symptom of disease, the intelligent sportsman will soon be able to arrive at the proximate cause of all this unnatural state of things, and then he will be competent to administer such remedies as may seem most likely to afford relief. Without these precautions, however, he would often be groping in the dark, and, consequently, not unfrequently, apply those remedies more calculated to aggravate than cure the malady.

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Skeleton of a dog

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24th Feb. 1814

. — A pug was accustomed to howl frequently when his young master played on the flute. If the higher notes were sounded, he would leap on his master's lap, look in his face, and howl vehemently. To-day the young man purposely blew the shrillest sound that he could. The dog, after howling three or four times, began to run round the room, and over the tables and chairs, barking incessantly. This he continued more than an hour.

When I saw him all consciousness of surrounding objects was gone. He was still running feebly, but barking might and main.

I dashed a basin of cold water in his face, and he dropped as if he had been shot. He lay motionless nearly a minute, and then began to struggle and to bark; another cup of water was dashed in his face, and he lay quite motionless during two minutes or more. In the mean time I had got a grain each of calomel and tartar emetic, which I put on his tongue, and washed it down with a little water. He began to recover, and again began to yelp, although much softer; but, in about a quarter of an hour, sickness commenced, and he ceased his noise. He vomited three or four times, and lay frightened and quiet. A physic-ball was given him in the evening, and on the following morning.

On the next day the young man put open the door, and sat himself down, and began to prepare the flute; the dog was out in a moment, and did not return during a couple of hours. On the following day he made his escape again, and so the matter went on; but before the expiration of the week, his master might play the flute if he pleased.

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This is a singular disease prevalent among cattle, but only occasionally seen in the dog. He becomes listless, dull, off his food, and scarcely recognises any surrounding object. He has no fit, but he wanders about the room fur several hours at a time, generally or almost invariably in the same direction, and with his head on one side. At first he carefully avoids the objects that are in his way; but by degrees his mental faculties become impaired; his sense of vision is confused or lost, and he blunders against everything: in fact, if uninterrupted, he would continue his strange perambulation incessantly, until he was fairly worn out and died in convulsions.

I used to consider the complaint to be uniformly fatal. I have resorted to every remedial measure that the case could suggest. I have bled, and physicked and setoned, and blistered, and used the moxa; but all without avail, for not in a single case did I save my patient.

No opportunity of

post-mortem

examination was lost. In some cases I have found spicula projecting from the inner plate of the skull, and pressing upon or even penetrating the

dura mater

. I know not why the dog should be more subject to these irregularities of cranial surface than any of our other patients; but decidedly he is so, and where they have pressed upon the brain, there has been injection of the membranes, and sometimes effusion between them.

In some cases I have found effusion without this external pressure, and, in some cases, but comparatively few, there has not been any perceptible lesion. Hydatids have been found in the different passages leading to the cranium, but they have not penetrated.

I used to recommend that the dog should be destroyed; but I met with two or three favourable cases, and, after that, I determined to try every measure that could possibly be serviceable. I bled, and physicked, and inserted setons, and tried to prevent the utter exhaustion of the animal. When he was unable longer to perform his circumvolutions, and found that he was foiled, he laid himself down, and by degrees resumed his former habits. He was sadly impatient and noisy; but in a few cases he was cured.

We have seen but two or three cases of this disease in dogs, are led to believe that it is quite uncommon with our domestic animals. One case in a valuable setter came on suddenly, and without any apparent cause (except perhaps over-feeding), and terminated fatally in the course of a few days. — L.

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in the dog assumes a most fatal character. It is an accompaniment, or a consequence, of almost every other disease. When the puppy is undergoing the process of dentition, the irritation produced by the pressure of the tooth, as it penetrates the gum, leads on to epilepsy. When he is going through the stages of distemper, with a very little bad treatment, or in spite of the best, fits occur. The degree of intestinal irritation which is caused by worms, is marked by an attack of epilepsy. If the usual exercise be neglected for a few days, and the dog is taken out, and suffered to range as he likes, the accumulation of excitability is expended in a fit.

The dog is, without doubt, the most intellectual animal. He is the companion and the friend of man: he exhibits, and is debased by some of his vices; but, to a greater degree than many will allow, he exhibits all the intelligence and the virtues of the biped. In proportion to his bulk, the weight of his brain far exceeds that of any other quadruped — the very smallest animals alone being excepted, in whom there must be a certain accumulation of medullary matter in order to give origin to the nerves of every system, as numerous in the minutest as in him of greatest bulk.

As it has been said of the human being that great power and exertion of the mental faculties are sometimes connected with a tendency to epilepsy, and, as violent emotions of joy or of grief have been known to be followed by it, I can readily account for its occurrence in the young dog, when frightened at the chiding of his master, or by the dread of a punishment which he was conscious that he had deserved. Then, too, I can understand that, when breaking loose from long confinement, he ranges in all the exuberance of joy; and especially when he flushes almost his first covey, and the game falls dead before him, his mental powers are quite overcome, and he falls into an epileptic fit.

The

treatment of epilepsy in the dog is simple, yet often misunderstood. It is connected with distemper in its early stage. It is the produce of inflammation of the mucous passages generally, which an emetic and a purgative will probably, by their direct medicinal effect, relieve, and free the digestive passages from some source of irritation, and by their mechanical action unburthen the respiratory ones.

When it is symptomatic of a weak state of the constitution, or connected with the after stages of distemper, the emeto-purgative must be succeeded by an anodyne, or, at least, by that which will strengthen, but not irritate the patient.

A

seton

is an admirable auxiliary in epilepsy connected with distemper; it is a counter-irritant and a derivative, and its effects are a salutary discharge, under the influence of which inflammation elsewhere will gradually abate.

I should, however, be cautious of

bleeding

in distemper fits. I should be fearful of it even in an early stage, because I well know that the acute form of that general mucous inflammation soon passes over, and is succeeded by a debility, from the depression of which I cannot always rouse my patient. When the fits proceed from dentition, I lance the jaws, and give an emetic, and follow it up with cooling purgative medicine. When they are caused by irregular and excessive exercise, I open the bowels and make my exercise more regular and equable. When they arise from excitation, I expose my patient more cautiously to the influence of those things which make so much impression on his little but susceptible mind.

If the fit has resisted other means, bleeding should be resorted to. A fit in other animals is generally connected with dangerous determination of blood to the head, and bleeding is imperative. A fit in the dog may be the consequence of sudden surprise and irritation. If I had the means I should see whether I could not break the charm; whether I could not get rid of the disturbance, by suddenly affecting the nervous system, and the system generally, in another way. I would seize him by the nape of the neck, and, with all my force, dash a little cold water in his face. The shock of this has often dispersed the epileptic agency, as it were by magic. I would give an emeto-purgative; a grain or a grain and a half of calomel and the same quantity of tartar emetic: I would soothe and coax the poor animal. Then, — and if I saw it at the beginning, I would do it early, — if the fit was more dependent upon, or was beginning to be connected with, determination of blood to the head, and not on any temporary cause of excitation or irritation, I would bleed freely from the jugular.

The

following singular case of epilepsy is narrated by M.W. Leblanc:

A dog of small size, three years old, was very subject to those epileptic fits that are so frequent among dogs. After a considerable period, the fits would cease, and the animal recover the appearance of perfect health; but the more he advanced in age the more frequent were the fits, which is contrary to that which usually happens.

The last fit was a very strong one, and was followed by peculiar symptoms. The animal became dispirited. The eyes lost their usual lively appearance, and the eyelids were often closed. The dog was very drowsy, and, during sleep, there were observed, from time to time, spasmodic movements, principally of the head and chest.

He always lay down on the left side

. When he walked, he had a marked propensity to turn to the left.

M. Leblanc employed purgatives, a seton to the back part of the neck, and the application of the cautery to the left side of the forehead; but nothing would stop the progress of the disease, and he died in the course of two months after the last fit. The nearer he approached his end the smaller were the circles that he took; and, in the latter part of his existence, he did little more than turn as if he were on a pivot, and, when the time arrived that he could walk no more, he used to lay himself down on the right side.

On the

post-mortem

examination, a remarkable thickness of the meninges was found on almost the whole of the left lobe of the brain. The

dura mater

, the two leaves of the arachnoid membrane, and the

pia mater

did not constitute more than one membrane of the usual thickness, and presented a somewhat yellow colouring. The cerebral substance of the left lobe appeared to be a little firmer than that of the right lobe. The fissures of the cerebral devolutions were much less deep than those of the other side The red vessels which ran in the fissures were of smaller size, and in some places could scarcely be discovered.

Confinement, over-feeding, blows on the head or spine, drying up of old ulcers, repelling of cutaneous affections, or, in fact, anything that is liable to derange the general health of the animal, will produce epileptic fits.We formerly had a beagle hound of very active temperament, which we were necessarily obliged to keep much confined while in the city; and to restrain her from running too wildly when taken into the streets, we were in the habit of coupling her with a greyhound of much milder disposition. Not being willing to submit lamely to this unpleasant check upon her liberty, she was ever making fruitless attempts to escape, either by thrusting herself forwards, or obstinately pulling backwards. These efforts resulted on several occasions in fits, produced by congestion of the brain, owing to the pressure of the collar on the neck, thereby interrupting the circulation, and inducing an influx of blood to those parts. We were ultimately obliged to abandon this method of restraint, which nearly proved fatal to our much-admired beagle: she being suddenly seized with one of these fits on a hot summer's day in one of our principal thoroughfares, the crowd of ignorant bystanders concluded it to be a case of rabies, and nothing but my taking her up in my arms, and carrying her from the scene of action, saved her from falling a victim to their ignorance.If the disease appears dependent upon plethora the result of confinement and gross living, the animal must be reduced by bleeding and purging, low diet, and exercise. If, however, the malady proceeds from weakness, as is sometimes the case in bitches while suckling a large litter, it will be necessary to relieve her of some of the pups, and supply her with the most nutritious diet, as also administer tonic balls; the following will answer.[Symbol: Rx]: Extract of Gentian, Quassia, ââ (each) grs. V, made into two pills, and one or two given morning and evening;or,[Symbol: Rx]: Powdered Columbo. Carbonate of Iron, ââ , grs. V, made into two pills, and one given morning and evening, or more frequently if desirable.A seton placed in the pole will often prevent these attacks, particularly when depending upon slight cerebral irritation, accompanying distemper and mange. Blisters and frictions to the spine are also serviceable. — L.

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This is an irregular reception or distribution of nervous power — a convulsive involuntary twitching of some muscle or set of muscles. It is an occasional consequence of distemper that has been unusually severe or imperfectly treated, and sometimes it is seen even after that disease has existed in its mildest form.

This nervous affection, more commonly known as St. Vitus' dance, is not a rare disease, and we doubt not that examples of it have been seen by most of our readers, more particularly in young dogs affected with distemper.This malady is characterized by sudden involuntary twitchings of the different muscles of the body, the disease being sometimes confined to one limb, sometimes to two, and frequently pervades the whole system, giving the dog a distressing and painful appearance. These involuntary motions, it is very true, are generally restricted during sleep, although in old chronic cases of long standing they often continue in full activity without any remission whatever. The disease is not attended with fever, and all the functions generally remain for a considerable time unimpaired. — L.

It first appears in one leg or shoulder, and is long, or perhaps entirely, confined to that limb. There is a singular spasmodic jerking action of the limb. It looks like a series of pulsations, and averages from forty to sixty in a minute. Oftener, perhaps, than otherwise, both legs are similarly affected. When the animal is lying down, the legs are convulsed in the way that I have described, and when he stands there is a pulsating depressing or sinking of the head and neck. In some cases, the muscles of the neck are the principal seat of the disease, or some muscle of the face; the temporal muscle beating like an artery; the masseter opening and closing the mouth, the muscles of the eyelid, and, in a few cases, those of the eye itself being affected. These convulsive movements generally, yet not uniformly, cease during sleep, but that sleep is often very much disturbed. If the case is neglected, and the dog is in a debilitated state, this spasmodic action steals over the whole frame, and he lies extended with every limb in constant and spasmodic action.

In

the majority of cases, such an expenditure of nervous and muscular power slowly destroys the strength of the animal, and he dies a mere skeleton; or the disease assumes the character of epilepsy, or it quiets down into true palsy.

In the most favourable cases, no curative means having been used, the dog regains his flesh and general strength; but the chorea continues, the spasmodic action, however, being much lessened. At other times, it seems to have disappeared; but it is ready to return when the animal is excited or attacked by other disease. In a variety of instances, there is the irritable temper which accompanies chorea in the human being, and most certainly when the disease has been extensive and confirmed.

Chorea, neglected or improperly treated, or too frequently pursuing its natural course, degenerates into

paralysis agitans

. There is a tremulous or violent motion of almost every limb. The spasms are not relaxed, but are even increased during sleep, and when the animal awakes, he rises wilh agitation and alarm. There is not a limb under the perfect control of the will; there is not a moment's respite; the constitution soon sinks, and the animal dies. No person should be induced to undertake the cure of such a case: the owner should be persuaded to permit a speedy termination to a life which no skill can render comfortable.

Chorea is oftenest observed in young dogs, and especially after distemper; and it seems to depend on a certain degree of primary or sympathetic inflammatory affection of the brain.

Chorea is often very plainly a consequence of debility: either the distribution of nervous power is irregular, or the muscles have lost their power of being readily acted upon, or have acquired a state of morbid irritability. The latter is the most frequent state. Their action is irregular and spasmodic, and it resembles the struggles of expiring nature far more than the great and uniform action of health. It is not the chorea that used to be described, in which there was an irresistible impulse to excessive action, and which was best combated by complete muscular exhaustion; but the foundation of this disease is palpable debility.

Rickets, bad feeding, cold and damp housing, worms in the alimentary canal, mange, and other chronic affections, are all forerunners of this malady. — L.

In the treatment of chorea there must be no bleeding, no excessive purgation, but aperients or alteratives, merely sufficient to keep the fæces in a pultaceous state, so as to carry off any source of irritation to the intestinal canal, and particularly some species of worms, too frequent sources of irritation there. To these should be added nutritious food, gentle exercise, tonic medicines, and general comforts. Counter-irritants may be applied — such as blisters over the head, and setons, extending from poll to poll — the application of turpentine, or the tincture of cantharides; but all of these will frequently be of no effect, and occasionally a rapid and fearful increase of irritability will ensue: antispasmodics are in this case of no use, and narcotics are altogether powerless. As for tonics, iron and gentian have been serviceable to a certain extent, but they have never cured the complaint.


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