The distemper is clearly a disease of the mucous membranes, usually commencing in the membrane of the nose, and resembling nasal catarrh.
In
the early stage it is
coryza
, or nasal catarrh; but the affection rapidly extends, and seems to attack the mucous membranes generally, determined to some particular one, either by atmospheric influence or accidental causes, or constitutional predisposition. The fits arise from general disturbance of the system, or from the proximity of the brain to the early seat of inflammation.
This account of the nature and treatment of distemper will, perhaps, be unsatisfactory to some readers. One thing, however, is clear, that for a disease which assumes such a variety of forms, there can be no specific; yet there is not a keeper who is not in possession of some supposed infallible nostrum. Nothing can be more absurd. A disease attacking so many organs, and presenting so many and such different symptoms, must require a mode of treatment varying with the organ attacked and the symptom prevailing. The faith in these boasted specifics is principally founded on two circumstances — atmospheric influence and peculiarity of breed. There are some seasons when we can scarcely save a dog; there are others when we must almost wilfully destroy him in order to lose him. There are some breeds in which, generation after generation, five out of six die of distemper, while there are others in which not one out of a dozen dies. When the season is favourable, and the animal, by hereditary influence, is not disposed to assume the virulent type of the disease, these two important agents are overlooked, and the immunity from any fatal result is attributed to medicine. The circumstances most conducive to success will be the recollection that it is a disease of the mucous surfaces, and that we must not carry the depleting and lowering system too far. Keeping this in view, we must accommodate ourselves to the symptoms as they arise.
The
natural medicine of the dog seems to be an emetic. The act of vomiting is very easily excited in him, and, feeling the slightest ailment, he flies to the dog-grass, unloads his stomach, and is at once well. In distemper, whatever be the form which it assumes, an emetic is the first thing to be given. Common salt will do when nothing else is at hand; but the best emetic, and particularly in distemper, consists of equal parts of calomel and tartar emetic. From half a grain to a grain and a half of each will constitute the dose.
This will act first as an emetic, and afterwards as a gentle purgative.
Then
, if the cough is urgent, and there is heaving at the flanks, and the nose is hot, a moderate quantity of blood may be taken — from three to twelve ounces — and this, if there has been previous constipation, may be followed by a dose of sulphate of magnesia, from two to six drachms.
In slight cases this will often be sufficient to effect a cure: but, if the dog still droops, and particularly if there is much huskiness, the antimonial or James's powder, nitre and digitalis, in the proportion of from half a grain to a grain of digitalis, from two to five grains of the James's powder, and from a scruple to a drachm of nitre, should be administered twice or thrice in a day. If on the third or fourth day the huskiness is not quite removed, the emetic should be repeated.
In
these affections of the mucous membranes, it is absolutely necessary to avoid or to get rid of every source of irritation, and worms will generally be found a very considerable one in young dogs. If we can speedily get rid of them, distemper will often rapidly disappear; but, if they are suffered to remain, diarrhœa or fits are apt to supervene: therefore some worm medicine should be administered.
I have said that vomiting is very easily excited in the dog; and that for this reason we are precluded from the use of a great many medicines in our treatment of him. Calomel, aloes, jalap, scammony, and gamboge will generally produce sickness.
We
are, therefore, driven to some mechanical vermifuge; and a very effectual one, and that will rarely fail of expelling even the tape-worm, is tin filings or powdered glass. From half a drachm to a drachm of either may be advantageously given twice in the day. There may generally be added to them digitalis, James's powder, and nitre, made into balls with palm oil and a little linseed meal. This course should be pursued in usual cases until two or three emetics have been given, and a ball morning and night on the intermediate days. Should the huskiness not diminish after the first two or three days, if the dog has not rapidly lost flesh, I should be disposed to take a little more blood, and to put a seton in the poll. It should be inserted between the ears, and reaching from ear to ear.
When there is fever and huskiness, and the dog is not much emaciated, a seton is an excellent remedy; but, if it is used indiscriminately, and when the animal is already losing ground, and is violently purging, we shall only hasten his doom, or rather make it more sure.
It is now, if ever, that pneumonia will be perceived. The symptoms of inflammation in the lungs of the dog can scarcely be mistaken. The quick and laborious breathing, the disinclination or inability to lie down, the elevated position of the head, and the projection of the muzzle, will clearly mark it. More blood must be subtracted, a seton inserted, the bowels opened with Epsom salts, and the digitalis, nitre, and James's powder given more frequently and in larger doses than before.
Little aid is to be derived from observation of the pulse of the dog; it differs materially in the breed, and size, and age of the animal. Many years' practice have failed in enabling me to draw any certain conclusion from it. The best place to feel the pulse of the dog is at the side. We may possibly learn from it whether digitalis is producing an intermittent pulse, which it frequently will do, and which we wish that it should do: it should then be given a little more cautiously, and in smaller quantities.
If the pneumonia is evidently conquered, or we have proceeded thus far without any considerable inflammatory affection of the chest, we must begin to change our plan of treatment. If the huskiness continues, and the discharge from the nose is increased and thicker, and the animal is losing flesh and becoming weak, we must give only half the quantity of the sedative and diuretic medicine, and add some mild tonic, as gentian, chamomile, and ginger, with occasional emetics, taking care to keep the bowels in a laxative but not purging state. The dog should likewise be urged to eat; and, if he obstinately refuses ail food, he should be forced with strong beef jelly, for a very great degree of debility will now ensue
We have thus far considered the treatment of distemper from its commencement; but it may have existed several days before we were consulted, and the dog may be thin and husky, and refusing to eat. In such case we should give an emetic, and then a dose of salts, and after that proceed to the tonic and fever balls.
Should the strength of the animal continue to decline, and the discharge from the nose become purulent and offensive, the fever medicine must be omitted, and the tonic balls, with carbonate of iron, administered. Some veterinary surgeons are very fond of gum resins and balsams. Mr.
Blaine
, in his excellent treatise on the distemper in his
Canine Pathology
, recommends myrrh and benjamin, and balsam of Peru and camphor. I much doubt the efficacy of these drugs. They are beginning to get into disrepute in the practice of human medicine; and I believe that if they were all banished from the veterinary
Materia Medica
we should experience no loss. When the dog begins to recover, although not so rapidly as we could wish, the tonic balls, without the iron, may be advantageously given, with now and then an emetic, if huskiness should threaten to return; but mild and wholesome food, and country or good air, will be the best tonics.
If the discharge from the nose become very offensive, the lips swelled and ulcerated, and the breath fetid, half an ounce of yeast may be administered every noon, and the tonics morning and night; and the mouth should be frequently washed with a solution of chloride of lime.
At this period of the disease the sub-maxillary glands are sometimes very much enlarged, and a tumour or abscess is formed, which, if not timely opened, breaks, and a ragged, ill-conditioned ulcer is formed, very liable to spread, and very difficult to heal. It is prudent to puncture this tumour as soon as it begins to point, for it will never disperse. After the opening, a poultice should be applied to cleanse the ulcer; after which it should be daily washed with the compound tincture of benjamin, and dressed with calamine ointment. Some balls should be given, and the animal liberally fed.
Should
the fits appear in an early stage, give a strong emetic; then bleed, and open the bowels with five or six grains of calomel and a quarter grain of opium: after this insert a seton, and then commence the tonic balls.
The progress of fits in the early stages of the disease may thus be arrested. The occurrence of two or three should not make us despair; but, if they occur at a later period, and when the dog is much reduced, there is little hope. This additional expenditure of animal power will probably soon carry him off. All that is to be done, is to administer a strong emetic, obviate costiveness by castor oil, and give the tonic balls with opium.
Of
the treatment of the yellow disease little can be said; we shall not succeed in one case in twenty. When good effect has been produced, it has been by one large bleeding, opening the bowels well with Epsom salts, and then giving grain doses of calomel twice a day in a tonic ball.
While
it is prudent to obviate costiveness, we should recollect that there is nothing more to be dreaded, in every stage of distemper, than diarrhœa. The purging of distemper will often bid defiance to the most powerful astringents. This shows the folly of giving violent cathartics in distemper; and, when I have heard of the ten, and twenty, and thirty grains of calomel that are sometimes given, I have thought it fortunate that the stomach of the dog is so irritable. The greater part of these kill-or-cure doses is ejected, otherwise the patient would soon be carried off by super-purgation. There is an irritability about the whole of the mucous membrane that may be easily excited, but cannot be so readily allayed; and, therefore, except in the earliest stage of distemper, or in fits, or limiting ourselves to the small portion of calomel which enters into our emetic, I would never give a stronger purgative than castor-oil or Epsom salts. It is of the utmost consequence that the purging of distemper should be checked as soon as possible.
In some diseases a sudden purging, and even one of considerable violence, constitutes what is called the crisis. It is hailed as a favourable symptom, and from that moment the animal begins to recover; but this is never the case in distemper: it is a morbid action which is then going on, and which produces a dangerous degree of debility.
The proper treatment of purging in cases of distemper, is first to give a good dose of Epsom salts, in order to carry away anything that may offend, and then to ply the animal with mingled absorbents and astringents. A scruple of powdered chalk, ten grains of catechu, and five of ginger, with a quarter of a grain of opium, made into a ball with palm oil, may be given to a middle-sized dog twice or thrice every day. To this may be added injections of gruel, with the compound chalk mixture and opium.
When the twitchings which I have described begin to appear, a seton is necessary, whatever may be the degree to which the animal is reduced. Some stimulating embrocation, such as tincture of cantharides, may be rubbed along the whole course of the spine; and the medicine which has oftenest, but not always, succeeded, is castor-oil, syrup of buckthorn, and syrup of white poppies, given morning and night, and a tonic ball at noon. If the dog will not now feed, he should be forced with strong soup. As soon, however, as the spasms spread over him, accompanied by a moaning that increases to a cry, humanity demands that we put an end to that which we cannot cure. Until this happens I would not despair; for many dogs have been saved that have lain several days perfectly helpless.
As
to the
chorea
which I have mentioned as an occasional sequel of distemper, if the dog is in tolerable condition, and especially if he is gaining flesh, and the spring or summer is approaching, there is a chance of his doing well. A seton is the first thing; the bowels should be preserved from constipation; and the nitrate of silver, in doses of one-eighth of a grain, made into a pill with linseed meal, and increased to a quarter of a grain, should be given morning and night.
We should never make too sure of the recovery of a distempered dog, nor commit ourselves by too early a prognosis. It is a treacherous disease; the medicines should be continued until every symptom has fairly disappeared; and for a month at least.
It
may be interesting to add the following account of the distemper in dogs, by Dr. Jenner. Several of our modern writers have copied very closely from him.
"That disease among dogs which has familiarly been called thedistemper, has not hitherto, I believe, been, much noticed by medical men. My situation in the country favouring my wishes to make some observations on this singular malady, I availed myself of it, during several successive years, among a large number of foxhounds belonging to the Earl of Berkeley; and, from observing how frequently it has been confounded with hydrophobia, I am induced to lay the result of my inquiries before the Medical and Chirurgical Society. It may be difficult, perhaps, precisely to ascertain the period of its first appearance in Britain. In this and the neighbouring counties, I have not been able to trace it back beyond the middle of the last century; but it has since spread universally. I knew a gentleman who, about forty-five years ago, destroyed the greater part of his hounds, from supposing them mad, when the distemper first broke out among them; so little was it then known by those most conversant with dogs. On the continent I find it has been known for a much longer period; it is as contagious among dogs as the small-pox, measles, or scarlet fever among the human species; and the contagiousmiasmata, like those arising from the diseases just mentioned, retain their infectious properties a long time after separation from the distempered animal. Young hounds, for example, brought in a state of health into a kennel, where others have gone through the distemper, seldom escape it. I have endeavoured to destroy the contagion by ordering every part of a kennel to be carefully washed with water, then whitewashed, and finally to be repeatedly fumigated with the vapour of marine acid, but without any good result."The dogs generally sicken early in the second week after exposure to the contagion; it is more commonly a violent disease than otherwise, and cuts off at least one in three that are attacked by it. It commences with inflammation of the substance of the lungs, and generally of the mucous membrane of thebronchi. The inflammation at the same time seizes on the membranes of the nostrils, and those lining the bones of the nose, particularly the nasal portion of the ethmoid bone. These membranes are often inflamed to such a degree as to occasion extravasation of blood, which I have observed coagulated on their surface. The breathing is short and quick, and the breath is often fetid; the teeth are covered with a dark mucus. There is frequently a vomiting of a glairy fluid. The dog commonly refuses food, but his thirst seems insatiable, and nothing cheers him like the sight of water. The bowels, although generally constipated as the disease advances, are frequently affected with diarrhœa at its commencement. The eyes are inflamed, and the sight is often obscured by mucus secreted from the eyelids, or by opacity of the cornea. The brain is often affected as early as the second day after the attack; ihe animal becomes stupid, and his general habits are changed. In this state, if not prevented by loss of strength, he sometimes wanders from his home. He is frequently endeavouring to expel by forcible expirations the mucus from the trachea and fauces, with a peculiar rattling noise. His jaws are generally smeared with it, and it sometimes flows out in a frothy state, from his frequent champing."During the progress of the disease, especially in its advanced stages, he is disposed to bite and gnaw anything within his reach; he has sometimes epileptic fits, and a quick succession of general though slight convulsive spasms of the muscles. If the dog survive, this affection of the muscles continues through life. He is often attacked with fits of a different description; he first staggers, then tumbles, rolls, cries as if whipped, and tears up the ground with his teeth and fore feet: he then lies down senseless and exhausted. On recovering, he gets up, moves his tail, looks placid, comes to a whistle, and appears in every respect much better than before the attack. The eyes, during this paroxysm, look bright, and, unless previously rendered dim by mucus, or opacity of the cornea, seem as if they were starting from their sockets. He becomes emaciated, and totters from feebleness in attempting to walk, or from a partial paralysis of the hind legs. In this state he sometimes lingers on till the third or fourth week, and then either begins to show signs of returning health (which seldom happens when the symptoms have continued with this degree of violence), or expires. During convalescence, he has sometimes, though rarely, profuse hæmorrhage from the nose."When the inflammation of the lungs is very severe, he frequently dies on the third day. I know one instance of a dog dying within twenty-four hours after the seizure; and in that short space of time the greater portion of the lungs was, from exudation, converted into a substance nearly as solid as the liver of a sound animal. In this case the liver itself was considerably inflamed, and the eyes and flesh universally were tinged with yellow, though I did not observe anything obstructing the biliary ducts. In other instances I have also observed the eyes looking yellow."The above is a description of the disease in its several forms; but in this, as in the diseases of the human body, there is every gradation in its violence."There is also another affinity to some human diseases, viz., that the animal which has once gone through it very rarely meets with a second attack. Fortunately this distemper is not communicable to man. Neither the effluvia from the diseased dog nor the bite have proved in any instance infectious; but, as it has often been confounded with canine madness, as I have before observed, it is to be wished that it were more generally understood; for those who are bitten by a dog in this state are sometimes thrown into such perturbation that hydrophobia symptoms have actually arisen from the workings of the imagination. Mr. John Hunter used to speak of a case somewhat of this description in his lectures."Agentleman who received a severe bite from a dog, soon after fancied the animal was mad. He felt a horror at the sight of liquids, and was actually convulsed on attempting to swallow them. So uncontrollable were his prepossessions, that Mr. Hunter conceived he would have died had not the dog which inflicted the wound been found and brought into his room in perfect health. This soon restored his mind to a state of tranquillity. The sight of water no longer afflicted him, and he quickly recovered."2
Palsy
, more or less complete, is sometimes the termination of the distemper in dogs.
It is usually accompanied by chorea, and it is then, in the majority of cases, hopeless. Setons should be inserted in the poll, being then, as nearly as possible, at the commencement of the spinal cord. They should be well stimulated and worn a considerable time. If they fail, a plaster composed of common pitch, with a very small quantity of yellow wax and some powdered cantharides, spread on sheep's-skin, should be placed over the whole of the lumbar and sacral regions, extending half-way down the thigh on either side. The bowels should be kept open by mild aperients, in order that every source of irritation may be removed from the intestinal canal. Some mild and general tonic will likewise be useful, such as gentian and ginger.
Footnote 1:
The following is a very frequent and unexaggerated history of distemper, when calomel has been given in too powerful doses:
August 30, 1828
. — A spaniel, six months old, has been ailing a fortnight, and three doses of calomel have been given by the owner. He has violent purging, with tenesmus and blood. Half an ounce of caster-oil administered.
31st.
Astringents, morning, noon, and night.
Sept. 6.
The astringents have little effect, or, if the purging is restrained one day, it returns with increased violence on the following day. Getting rapidly thin. Begins to husk. Astringents continued.
10th.
The purging is at last overcome, but the huskiness has rapidly increased, accompanied by laborious and hurried respiration. — Bleed to the extent of three ounces.
11th.
The breathing relieved, but he obstinately refuses to eat, and is forced several times in the day with arrow-root or strong soup.
18th.
He had become much thinner and weaker, and died in the evening. No appearance of inflammation on the thoracic viscera, nor in any part of the alimentary canal. The intestines are contracted through the whole extent.
Veterinarian
, ii. 290.
return to footnote mark
Footnote 2:
Medico-Chirurgical Transitions
, 31st March, 1809.
return
Contents/Detailed Contents, p. 7/Index
In 1809, there was observed, at the Royal Veterinary School at Lyons, an eruptive malady among the dogs, to which they gave the name of
small-pox
. It appeared to be propagated from dog to dog by contagion. It was not difficult of cure; and it quickly disappeared when no other remedies were employed than mild aperients and diaphoretics. A sheep was inoculated from one of these dogs. There was a slight eruption of pustules formed on the place of inoculation, but nowhere else; nor was there the least fever.
At another time, also, at the school at Lyons, a sheep died of the regular sheep-pox. A part of the skin was fastened, during four-and-twenty hours, on a healthy sheep, and the other part of it on a dog, both of them being in apparent good health. No effect was produced on the dog, but the sheep died of confluent sheep-pox.
The
essential symptoms
of small-pox in dogs succeed each other in the following order: the skin of the belly, the groin, and the inside of the fore arm, becomes of a redder colour than in its natural state, and sprinkled with small red spots irregularly rounded. They are sometimes isolated, sometimes clustered together. The near approach of this eruption is announced by an increase of fever.
On the second day the spots are larger, and the integument is slightly tumefied at the centre of each.
On the third day the spots are generally enlarged, and the skin is still more prominent at the centre.
On the fourth day the summit of the tumour is yet more prominent. Towards the end of that day, the redness of the centre begins to assume a somewhat gray colour. On the following days, the pustules take on their peculiar characteristic appearance, and cannot be confounded with any other eruption, On the summit is a white circular point, corresponding with a certain quantity of nearly transparent fluid which it contains, and covered by a thin and transparent pellicle. This fluid becomes less and less transparent, until it acquires the colour and consistence of pus. The pustule, during its serous state, is of a rounded form. It is flattened when the fluid acquires a purulent character, and even slightly depressed towards the close of the period of suppuration, and when that of desiccation is about to commence, which ordinarily happens towards the ninth or tenth day of the eruption. The desiccation and the desquamation occupy an exceedingly variable length of time; and so, indeed, do all the different periods of the disease. What is the least inconstant, is the duration of the serous eruption, which is about four days, if it has been distinctly produced and guarded from all friction. If the general character of the pustules is considered, it will be observed, that, while some of them are in a state of serous secretion, others will only have begun to appear.
The eruption terminates when desiccation commences in the first pustules; and, if some red spots show themselves at that period of the malady, they disappear without being followed by the development of pustules. They are a species of abortive pustules. After the desiccation, the skin remains covered by brown spots, which, by degrees, die away. There remains no trace of the disease, except a few superficial cicatrices on which the hair does not grow.
The
causes which produce the greatest variation in the periods of the eruption are, the age of the dog, and the temperature of the situation and of the season. The eruption runs through its different stages with much more rapidity in dogs from one to five months old than in those of greater age. I have never seen it in dogs more than eighteen months old. An elevated temperature singularly favours the eruption, and also renders it confluent and of a serous character. A cold atmosphere is unfavourable to the eruption, or even prevents it altogether. Death is almost constantly the result of the exposure of dogs having small-pox to any considerable degree of cold. A moderate temperature is most favourable to the recovery of the animal. A frequent renewal or change of air, the temperature remaining nearly the same, is highly favourable to the patient; consequently close boxes or kennels should be altogether avoided.
I
have often observed, that the perspiration or breath of dogs labouring under
variola
emits a very unpleasant odour. This smell is particularly observed at the commencement of the desiccation of the pustules, and when the animals are lying upon dry straw; for the friction of the bed against the pustules destroys their pellicles, and permits the purulent matter to escape; and the influence of this purulent matter is most pernicious. The fever is increased, and also the unpleasant smell from the mouth, and that of the fæces. In this state there is a disposition which is rapidly developed in the lungs to assume the character of pneumonia. This last complication is a most serious one, and almost always terminates fatally. It has a peculiar character. It shows itself suddenly, and with all its alarming symptoms. It is almost immediately accompanied by a purulent secretion from the bronchi, and the second day does not pass without the characters of pneumonia being completely developed. The respiration is accompanied by a mucous
râle
which often becomes sibilant. The nasal cavities are filled with a purulent fluid. The dog that coughs violently at the commencement of the disease, employs himself, probably, on the following day, in ejecting, by a forcible expulsion from the nostrils, the purulent secretion which is soon and plentifully developed. When he is lying quiet, and even when he seems to be asleep, there is a loud, stertorous, guttural breathing.
Contents/Detailed Contents, p. 7/Index
The existence of certain insects found burrowing under the skin of the human being, and of various tribes of animals, has been acknowledged from the 12th century. In the 17th century, correct engravings of these insects were produced. On the other hand many doubted their existence, because it had not been their lot to see them. In 1812, Galés, a pupil in the hospital of St. Louis, pretended to have found some of them. They were put into the hands of M. Raspail, of Paris, who proved that they were nothing more than the common cheese-mites; and substituted by Galés for those seen by Bonomo.
Professor Hertwig, of Berlin, has given a graphic sketch of these insects (
Veterinarian
, vol. xi. pp. 373, 489).
Mr. Holthouse states that,
"placed on the skin of a healthy individual, they excite a disease in the part to which they were confined, having all the characters of scabies; that insects taken from mangy sheep, horses, and dogs, and transplanted to healthy individuals of the same species, produce in them a disease analogous to that in the animals from which they were taken; and that there are too many well-attested cases on record to permit us to doubt of scabies having been communicated from animals to man.
Mange
may in some degree be considered as an hereditary disease. A mangy dog is liable to produce mangy puppies, and the progeny of a mangy bitch will certainly become affected sooner or later. In many cases a propensity to the disease will be speedily produced. If the puppies are numerous, and confined in close situations, the effluvia of their transpiration and fæcal discharges will often be productive of mange very difficult to be removed. Close confinement, salted food, and little exercise, are frequent causes of mange.
TheScabbyMange
is a frequent form which this disease assumes. It assumes a pustular and scabby form in the red mange, particularly in white-haired dogs, when there is much and painful inflammation. A peculiar eruption, termed
surfeit
, which resembles mange, is sometimes the consequence of exposure to cold after a hot sultry day. Large blotches appear, from which the hair falls and leaves the skin bare and rough. Acute mange sometimes takes on the character of erysipelas; at other times there is considerable inflammation. The animal exhibits heat and restlessness, and ulcerations of different kinds appear in various parts, superficial but extensive.
Bleeding
, aperient and cooling medicines are indicated, and also applications of the subacetate of lead, or spermaceti ointment. A weak infusion of tobacco may be resorted to when other things fail, but it must be used with much caution. The same may be said of all mercurial preparations. The tanner's pit has little efficacy, except in slight cases. Slight bleedings may be serviceable, and especially in full habits; setons may be resorted to in obstinate cases. A change in the mode of feeding will often be useful. Mild purgatives, and especially Epsom salts, are often beneficial, and also mercurial alternatives, as Æthiop's mineral with cream of tartar and nitre. The external applications require considerable caution. If mercury is used, care must be taken that the dog does not lick it. The diarrhœa produced by mercury often has a fatal effect.
Unguents
are useful, but considerable care must be taken in their application. They must be applied to the actual skin, not over the hair. In old and bad cases much time and patience will be requisite. Mr.
Blaine
had a favourite setter who had virulent mange five years. He was ordered to be dressed every day, or every second day, before the disease was complete conquered.
Cutaneous affections have lately been prevalent to an extent altogether unprecedented on this and on the other side of the channel. In the latter part of 1843 the disease assumed a character which had not been known among us for many years. The common mange, which we used to think we could easily grapple with, was now little seen: even the usual red mange with the fox-coloured stain was not of more frequent occurrence than usual, but an intolerable itchiness with comparatively little redness of skin, and rarely sufficient to account for the torture which the animal seemed to endure, and often with not the slightest discoloration of the integument, came before us almost every day, and under its influence the dog became ill-tempered, dispirited, and emaciated, until he sunk under its influence. All unguents were thrown away here. Lotions of corrosive sublimate, decoction of bark, infusion of digitalis or tobacco, effected some little good; but the persevering use of the iodide of potassium, purgatives, and the abstraction of blood very generally succeeded.