Chinaphenin, CO (NH·C6H4OC2H5) (C20H23N2O2) = C20H33N3O4, the quinine carbonic acid ester of phenetidin.
Actions and Uses.—Chinaphenin combines the antiperiodic properties of quinine with the analgesic power of phenacetin, with the advantage of tastelessness and asserted freedom from symptoms of cinchonism produced by the administration of the two remedies in simple mixture. It is recommended in febrile diseases, especially la grippe; in spasmodic conditions, such as whooping-cough; in certain forms of malaria and in neuralgia. Dosage.—Adult: 0·3 to 0·6 gramme (5 to 10 grains) ordinarily, 1·5 to 2 grammes (22 to 30 grains), given in two doses as an antipyretic in neuralgia and malaria; in whooping-cough: 0·13 to 0·3 gramme (2 to 5 grains), according to age. Manufactured by Farbenfabriken, vorm. Friedr. Bayer & Co., Elberfeld, Germany (Continental Color & Chemical Co., New York).